Publications by authors named "Fabio A Sierra"
Article Synopsis
- The study investigates how the Apoϵ gene, particularly the ϵ4 allele, interacts with cardio-metabolic and social risk factors in relation to cognitive impairment in Bogotá's elderly population.
- It analyzed 1,263 participants over 50 years old, categorizing them into groups based on their cognitive status and Apoϵ allele presence.
- Results indicated that while lower education, high blood pressure, and older age were associated with dementia, the ϵ4 allele mainly affected diabetic individuals with dementia, who tended to score lower on cognitive tests.
Merkel cell carcinoma (MCC) is a rare skin tumour of neuroendocrine origin with aggressive behaviour. The aims of this study were to investigate the association of p63 + MCC with clinicopathological features and to estimate survival through a systematic review and meta-analysis. A comprehensive search of PubMed, Embase, Scopus and Virtual Health Library following the PRISMA guidelines was conducted on September 2017.
View Article and Find Full Text PDFUnlabelled: The low prevalence of dementia described in communities is likely due to the low sensitivity of screening tests and an absence of evaluation by specialists.
Objective: To estimate the prevalence of mild cognitive impairment (MCI) and dementia in adults older than 50 years.
Methods: A two-phase, cross-sectional study was conducted by specialists to evaluate cognition and associated demographic risk factors in 1,235 independent community-dwelling adults from Bogotá.