Publications by authors named "Fabienne Dalla Vale"
Article Synopsis
- New technologies for managing type 1 diabetes (T1D) in young children are growing, but there’s a lack of real-life studies focused on kids under 6 years old.
- The study aimed to investigate parental satisfaction with continuous and flash glucose monitoring devices for T1D in children, involving 114 parents who completed a questionnaire.
- Results showed 95% of parents were satisfied with the monitoring devices, with satisfaction linked to the device's reliability, though some parents reported challenges related to applying the devices and skin reactions.
Article Synopsis
- The transition from pediatric to adult diabetes care for individuals with type 1 diabetes (T1D) is a challenging phase that needs more understanding, focusing on the experiences and satisfaction of young adults in France.
- An online survey was conducted with 104 participants to gather insights about their transition experience, revealing that many faced significant diabetes management issues post-transition.
- Key factors for a successful transition included early interactions with adult care teams, allowing participants to choose their transition age, and maintaining good diabetes control before leaving pediatric care.
Article Synopsis
- The study aimed to assess the long-term effects of using a hybrid closed loop (HCL) system on glucose levels and body mass index (BMI) in children with type 1 diabetes during puberty.* -
- Over 30 months, data showed that improvements in HbA1c levels were maintained and BMI scores remained stable in participants, with no severe hypoglycemic events and only one unrelated ketoacidosis case.* -
- Findings suggest that prolonged HCL usage can help manage glucose control during puberty without negatively affecting BMI in children with type 1 diabetes.*
Familial Renal Glucosuria (FRG) is a co-dominantly inherited trait characterized by orthoglycaemic glucosuria. From 2003 to 2015 we have reported several cohorts validating SLC5A2 (16p11.2), encoding SGLT2 (Na+/glucose cotransporter family member 2), as the gene responsible for FRG.
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- * It analyzed data from 60 children over four treatment phases, noting the percentage of time their glucose levels stayed in the target range while considering missed boluses.
- * Results indicate that HCL therapy consistently improved glycemic control compared to SAP, even when meal insulin was missed, suggesting HCL may be the better choice for managing diabetes in children.
Aim: To assess the safety and efficacy of hybrid closed-loop (HCL) insulin delivery 24/7 versus only evening and night (E/N), and on extended 24/7 use, in free-living children with type 1 diabetes.
Materials And Methods: Prepubertal children (n = 122; 49 females/73 males; age, 8.6 ± 1.
Objectives: The objective of this multicenter cross-sectional study was to determine predictors of poor glycaemic control in children with type 1 diabetes mellitus (T1DM), particularly with respect to socioeconomic status (SES).
Methods: Our study population consisted of 1154 children who attended T1DM follow-up consultation with a pediatric diabetes specialist. Clinical and demographic data were retrieved retrospectively from patients' records.
Is there an optimal strategy for real-time continuous glucose monitoring in pediatrics? A 12-month French multi-center, prospective, controlled randomized trial (Start-In!).
Pediatr Diabetes
May 2019
Aim: To compare the efficacy of three strategies for real-time continuous glucose monitoring (RT-CGM) over 12 months in children and adolescents with type 1 diabetes.
Methods: A French multicenter trial (NCT00949221) with a randomized, controlled, prospective, open, and parallel-group design was conducted. After 3 months of RT-CGM, patients were allocated to one of three groups: return to self-monitoring of blood glucose, continuous CGM (80% of the time), or discontinuous CGM (40% of the time).
Article Synopsis
- The study aimed to gather the opinions of children with type 1 diabetes on their daily use of flash glucose monitoring (FGM), specifically the FreeStyle Libre® system.
- A survey conducted in French medical centers revealed that a majority of participants had been using the sensor for over three months, mainly to avoid finger prick pain and allow parents to monitor nighttime glucose levels.
- Although most users reported satisfaction with FGM, they encountered challenges like sensor detachment and measurement errors, indicating the need for better training on its effective use for insulin management.
This randomized control trial investigated glucose control with closed-loop (CL) versus threshold-low-glucose-suspend (TLGS) insulin pump delivery in pre-pubertal children with type 1 diabetes in supervised hotel conditions. The patients [n = 24, age range: 7-12, HbA1c: 7.5 ± 0.
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- Mycoplasma pneumoniae could lead to kidney issues in kids, but severe cases like glomerulonephritis are rare; this report presents an unusual case in a 3-year-old girl.
- The girl experienced nephrotic syndrome and poor kidney function, with her serum C3 complement levels initially low but normalizing after treatment.
- Treatment involved high-dose steroids, plasmapheresis, and additional medication, resulting in remission and improved kidney health, but controversy exists regarding the best treatment approach for such cases.
Premature newborns are particularly vulnerable to iatrogenic hypothyroidism due to iodine exposure, usually through skin absorption of iodine-containing disinfectants or intravenous administration of iodinated contrast agents. We report here a case of severe iatrogenic hypothyroidism with goiter and cholestasis, discovered six weeks after a contrast enema using sodium ioxitalamate, an iodinated contrast agent. Prematurity, intrauterine growth retardation, and enteral feeding intolerance could explain why this complication occurred after contrast enema.
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