In silico experiments of intimal hyperplasia development: disendothelization in an axisymmetric idealized artery.

We use in silico experiments to study the role of the hemodynamics and of the type of disendothelization on the physiopathology of intimal hyperplasia. We apply a multiscale bio-chemo-mechanical model of intimal hyperplasia on an idealized axisymmetric artery that suffers two kinds of disendothelizations. The model predicts the spatio-temporal evolution of the lesions development, initially localized at the site of damages, and after few days displaced downstream of the damaged zones, these two stages being observed whatever the kind of damage.

Sudden diffusion of turbulent mixing layers in weakly coupled plasmas under compression.

The rapid growth of viscosity driven by temperature increase in turbulent plasmas under compression induces a sudden dissipation of kinetic energy, eventually leading to the relaminarization of the flow [Davidovits and Fisch, Phys. Rev. Lett.

Self-similar regimes of turbulence in weakly coupled plasmas under compression.

Turbulence in weakly coupled plasmas under compression can experience a sudden dissipation of kinetic energy due to the abrupt growth of the viscosity coefficient governed by the temperature increase. We investigate in detail this phenomenon by considering a turbulent velocity field obeying the incompressible Navier-Stokes equations with a source term resulting from the mean velocity. The system can be simplified by a nonlinear change of variable, and then solved using both highly resolved direct numerical simulations and a spectral model based on the eddy-damped quasinormal Markovian closure.

Turbulence and columnar vortex formation through inertial-wave focusing.

In this experimental and numerical study, we consider the role of inertial waves in the inverse energy cascade and the transfer of momentum in a rotating fluid. An oscillating torus generates two inertial-wave cones with their energy focusing at their apex. For high wave amplitudes, turbulence is generated locally around the focal point, resulting in angular momentum mixing and the generation of a columnar cyclonic vortex.