Publications by authors named "Fabiana de Oliveira Yamashita"
Article Synopsis
- Bothrops leucurus is a major cause of snakebites in Northeast Brazil, but its venom is not included in current antivenom production, prompting the exploration of alternative treatments.
- Chlorogenic acid and rosmarinic acid were studied for their ability to inhibit B. leucurus venom's enzymatic activity and harmful effects, showing significant effectiveness in reducing edema, hemorrhage, and myotoxicity in both in vitro and in vivo tests.
- The compounds demonstrated interactions with venom components and proved to be more effective than existing antivenoms, suggesting their potential as complementary treatments in snakebite management.
Mangaba (Hancornia speciosa Gomes) fruit juice decreases acute pulmonary edema induced by Tityus serrulatus venom: Potential application for auxiliary treatment of scorpion stings.
Fabiana de Oliveira Yamashita Manoela Torres-Rêgo Jacyra Antunes Dos Santos Gomes Juliana Félix-Silva Júlia Gabriela Ramos Passos
Toxicon
May 2020
Scorpionism represents a serious public health problem due to its increasing incidence. In Brazil, Tityus serrulatus is a species of major medical importance, especially in children and the elderly, as envenomation may induce serious acute pulmonary edema. "Mangaba" (Hancornia speciosa Gomes) fruit juice is popularly used in the treatment of several inflammatory disorders.
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