Are statins onco- suppressive agents for every type of tumor? A systematic review of literature.

Introduction: Statins, in the role of anti-cancer agents, have been used in many types of cancers with results in some cases promising while, in others, disappointing.

Areas Covered: The purpose of this review is to identify and highlight data from literature on the successes or failure of using statins as anti-cancer agents. We asked ourselves the following two questions:1.

Kikuchi-Fujimoto Disease: A Distinct Pathological Entity but also an "Overlap" Autoimmune Syndrome: A Systematic Review.

Background: The association between KFD and autoimmune diseases, not only with systemic lupus erythematosus, has been repeatedly described.

Objective: The aim of this review is to evaluate whether an overlap syndrome is present between KFD and autoimmune diseases, whether there is a chronological and a casual relationship between the pathologies.

Methods: The databases used for the overlap case search were Medline and Embase from which we extrapolated the studies of interest.