Publications by authors named "Fabiana Regina da Silva Olimpio"

Article Synopsis
  • Aerobic physical training (APT) has been shown to decrease eosinophilic airway inflammation in asthma, but its specific effects and mechanisms in severe cases are still not fully understood.
  • The study involved both in vitro experiments with human cells related to asthma and in vivo experiments with mice to observe the impact of APT on inflammatory markers and cell activity.
  • Results indicated that APT reduced various inflammatory cytokines and other immune cell activities, improved lung function, and increased levels of the anti-inflammatory molecule IL-10, indicating a potential therapeutic role in managing severe asthma.
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Collagen-based products are found in different pharmaceuticals, medicine, food, and cosmetics products for a wide variety of applications. However, its use to prevent or improve the health of skin is growing dizzyingly. Therefore, this study investigated whether collagen peptides could induce fibroblast and keratinocyte proliferation and activation beyond reducing an inflammatory response induced by lipopolysaccharide (LPS).

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Even after virus elimination, numerous sequelae of coronavirus disease 2019 (COVID-19) persist. Based on accumulating evidence, large amounts of proinflammatory cytokines are released to drive COVID-19 progression, severity, and mortality, and their levels remain elevated after the acute phase of COVID-19, playing a central role in the disease' sequelae. In this manner, bronchial epithelial cells are the first cells hyperactivated by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), leading to massive cytokine release, triggering the hyperactivation of leukocytes and other cells, and mediating COVID-19 sequelae.

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