Publications by authors named "Fabiana Pettenon"
Sinonasal neuroendocrine neoplasms (SN-NENs) are rare and mostly include neuroendocrine carcinoma (NEC), whereas neuroendocrine tumor (NET) is exceptional in this site. Olfactory neuroblastoma (ONB) is a malignant neuroectodermal neoplasm arising in the nasal cavity. Albeit crucial for correct patients' management, the distinction of high grade ONB from NEC is challenging and requires additional diagnostic markers.
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- Poorly differentiated sinonasal carcinomas (PDSNCs) are rare, aggressive tumors that include different types like squamous cell carcinoma and sinonasal undifferentiated carcinoma, with various epigenetic markers suggested for classification and prognosis.
- Recent studies have identified specific subtypes of sinonasal carcinomas linked to particular genetic mutations, indicating that these should be categorized as separate entities for better treatment strategies.
- A study of 53 PDSNC cases found a significant relationship between genetic defects and abnormal DNA methylation levels, which correlated with worse patient outcomes, highlighting the importance of genetic and epigenetic profiling in treatment planning.
Tracheal chondrosarcoma is an extremely rare, slow-growing, malignant tumour. This study aims to analyze the cases of tracheal chondrosarcoma published in the literature and our case report, in order to better define tracheal chondrosarcoma management. A systematic review of the English literature was carried out for fully described tracheal chondrosarcoma cases.
View Article and Find Full Text PDFBackground: The impact of menopause is a consequence of social, physical and mental changes; hormonal changes play an important role in inducing an increased risk of developing depressive symptoms. It is essential to treat mood and vasomotor symptoms and to prevent their onset to promote an improvement in the quality of life, both in terms of clinical and psychological conditions.
Objective: This observational study aims to compare paroxetine and vortioxetine in a sample of patients affected by postmenopausal depression attending the Anxiety and Depression Clinic in terms of: efficacy in determining clinical remission (HDRS ≤ 7) and tolerability; improvement of autonomic and cognitive symptoms.