Publications by authors named "Fabiana Deise Siman"
Article Synopsis
- Right ventricular function is crucial for predicting mortality and heart failure after a heart attack, but the underlying mechanisms of right ventricular dysfunction post-MI are not well understood.
- The study involved inducing heart attacks in rats and comparing those showing heart failure symptoms with those that don't, using isolated heart strips to assess RV contractility.
- Findings revealed that RV contractility was preserved in rats without heart failure due to increased expression of the SERCA-2a protein, suggesting that enhancing SERCA-2a levels could be a potential treatment strategy for heart failure.
