Association of Fusobacterium nucleatum Levels by ddPCR in Oral Rinse Samples With Periodontal Disease in Oral Squamous Cell Carcinoma Patients and in Controls.

Background: The role of microbiome, particularly Fusobacterium nucleatum (Fn), in periodontal disease and oral squamous cell carcinoma (OSCC) has been recently explored. This study aimed to evaluate the Fn presence and its levels in oral rinse samples from Brazilian OSCC patients and healthy individuals and its association with sociodemographic, clinical, and oral health features.

Methods: In this case-control study, 80 participants were included, 31 OSCC patients and 49 individuals without a cancer history.

Determinants of adherence to dental treatment of socially vulnerable adolescents: a cohort study.

Objective: Different studies with adolescents address the difficulty they have to adhere to oral dental treatments. Therefore, better understanding the processes involved in adherence to treatment in this population is necessary. The aim of this study was to investigate the factors that influence adherence to dental treatment in socially underprivileged adolescents in primary care.

Mutational Profiling of Driver Tumor Suppressor and Oncogenic Genes in Brazilian Malignant Pleural Mesotheliomas.

Background: Malignant pleural mesothelioma (MPM) is a highly lethal disease comprising a heterogeneous group of tumors with challenging to predict biological behavior. The diagnosis is complex, and the histologic classification includes 2 major subtypes of MPM: epithelioid (∼60% of cases) and sarcomatous (∼20%). Its identification depends upon pathological investigation supported by clinical and radiological evidence and more recently ancillary molecular testing.

Trend analysis of the quality indicators for the Brazilian cervical cancer screening programme by region and state from 2006 to 2013.

Background: Quality indicators for the Brazilian cervical cancer screening programme can provide a perspective on its effectiveness in Brazilian macro-regions and states. The aim of this study was to perform a trend analysis of the cervical cancer screening program's quality indicators, according to Brazilian regions and states, from 2006 to 2013.

Methods: Using information from approximately 62,000,000 exams obtained from the Information System of Cervical Cancer Screening (SISCOLO), joinpoint analysis was used to calculate the Annual Percentage Change (APC).

Organized Cervical Cancer Screening Program in Barretos, Brazil: Experience in 18 Municipalities of São Paulo State.

Objectives: The aim of this report is to demonstrate the Barretos Cancer Hospital initiative of organizational, laboratorial, and human resources training in the implementation of an organized cervical screening program in low-resource settings.

Methods: We developed a computational program to report all epidemiological, clinical, and laboratorial findings, and to trace all necessary information to recruit women for regular screening or for referral for complementary exams after liquid-based Pap test analyses.

Results: All Pap tests were collected in liquid medium and in 2014 more than 160,000 tests were analyzed and 2,900 colposcopy examinations were performed.

Retrospective analysis of breast cancer prognosis among young and older women in a Brazilian cohort of 738 patients, 1985-2002.

Invasive breast cancer (BC) is infrequent among women aged ≤40 years, however, the disease outlook in these younger patients is generally worse than among older women. The present study aimed to compare socio-demographic, clinical and pathological characteristics, and their association with long-term survival, between two random cohorts of young (≤40 years) and older (50-69 years) Brazilian patients with BC. The cohort comprised of 738 randomly selected women who were diagnosed with BC at Barretos Cancer Hospital, Pio XII Foundation (Barretos, Brazil) between January 1985 and December 2002; the patients included young women (n=376) and older women (n=362).

Racial/Ethnic Disparities in Cervical Cancer Screening and Outcomes.

Invasive cervical cancer disproportionately affects women without sufficient access to care, with higher rates among minority groups in higher-income countries and women in low-resource regions of the world. Many elements contribute to racial/ethnic disparities in the cervical cancer continuum - from screening and diagnosis to treatment and outcome. Sociodemographic factors, access to healthcare, income and education level, and disease stage at diagnosis are closely linked to such inequities.

Qualitative study on adolescents' reasons to non-adherence to dental treatment.

The study aimed to reflect on adolescents' speeches regarding their justifications for non-adherence to dental treatment. This is a qualitative research derived from a quantitative research aimed at adolescents from 15 to 19 years of public schools belonging to the area of 34 Primary Health Units - Family Health, in Piracicaba, SP, in 2012. The adolescents were evaluated, diagnosed and referred for dental treatment.

Individual and contextual factors related to dental caries in underprivileged Brazilian adolescents.

Background: Investigate the individual and contextual variables related to caries in underprivileged adolescents, and the disparity in distribution of the disease.

Methods: Cross-sectional analytical study, conducted in the city of Piracicaba, SP, Brazil, in 2012. The probabilistic sample was composed of 1,179 adolescents from 15-19 years of age, randomly selected from 21 state schools and 34 Primary Health Units--Family Health (PHU-FH).

Variables associated with the performance of Centers for Dental Specialties in Brazil.

The aim of this study was to evaluate the performance of the Centers for Dental Specialties (CDS) in the country and associations with sociodemographic indicators of the municipalities, structural variables of services and primary health care organization in the years 2004-2009. The study used secondary data from procedures performed in the CDS to the specialties of periodontics, endodontics, surgery and primary care. Bivariate analysis by χ2 test was used to test the association between the dependent variable (performance of the CDS) with the independents.

Evolution of post-deployment indicators of oral health on the Family Health Strategy.

Objective: To evaluate the evolution of indicators after the implementation of 21 Oral Healthcare Teams in the Family Health Strategy.

Methods: We used data from outpatient services of Oral Healthcare Teams to evaluate efficiency, access, percentage of absences and emergencies of oral healthcare professionals who worked in the partnership between the Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein and the Secretaria Municipal de Saúde de São Paulo, during the period 2009-2011.

Results: Percentages of emergencies, income, and access showed a significant difference during the period analyzed, but no difference for percentage of absences was found.

Quality of life and socio-dental impact among underprivileged Brazilian adolescents.

Purpose: To evaluate the influence of clinical variables, individual and contextual characteristics on the quality of life (QL) of underprivileged adolescents in a municipality in the interior of the State of São Paulo, Brazil.

Methods: An analytical cross-sectional study was conducted in Piracicaba, in 2012, with 1,172 adolescents aged 15-19 years, from 21 state schools and 34 Family Health Units. The dependent variables included the socio-dental impact (OIDP) and quality of life (WHOQOL-bref) indices.

[Impact variables on the decline in infant mortality in the state of São Paulo, Brazil: 1998-2008].

This is an ecological, analytical and retrospective study comprising the 645 municipalities in the State of São Paulo, the scope of which was to determine the relationship between socioeconomic, demographic variables and the model of care in relation to infant mortality rates in the period from 1998 to 2008. The ratio of average annual change for each indicator per stratum coverage was calculated. Infant mortality was analyzed according to the model for repeated measures over time, adjusted for the following correction variables: the city's population, proportion of Family Health Programs (PSFs) deployed, proportion of Growth Acceleration Programs (PACs) deployed, per capita GDP and SPSRI (São Paulo social responsibility index).

[Referencing and counter-referencing in specialized dental health procedures in Campinas in the state of São Paulo, Brazil].

This article aims to evaluate the referencing of the demand for specialized care in oral health in Campinas in relation to the distribution of treatment and the influence of socio-economic variables in addition to the perception and information available to users in relation to counter-referencing. It is an observational exploratory study, selecting two Health Administrative Regions: one with a Center for Dental Specialties and one without, divided into two phases: 1) all referrals to secondary care were collected from all Oral Health teams as well as population and socio-economic data and distribution of referrals; 2) interview with 331 users, checking the counter-referencing, quality of service and reasons for absences or withdrawals. Regarding the counter-referencing, the majority of users who received the specialized treatments were well attended, and waited less than one month for appointment scheduling.

Oral cancer calibration and diagnosis among professionals from the public health in São Paulo, Brazil.

Unlabelled: Oral cancer is a public health problem responsible for 13% of deaths worldwide in 2008 and screening programs can be useful to detect individuals more vulnerable to the disease, improving its prognosis.

Objectives: The aim of the present study was to evaluate oral cancer calibration (in lux and in vivo methodologies) and diagnosis processes performed by dental surgeons (DSs) of the public health system in São Paulo, Brazil.

Material And Methods: Thirty-three oral cancer photographs were examined during in lux calibration, while 560 individuals were examined during in vivo calibration.

[Prevention and detection of oral cancer: participatory planning as a strategy to broaden coverage in the elderly population].

With respect to addressing oral cancer as a public health problem and the need to conduct early diagnosis to ensure a favorable prognosis for patients, the city of Marilia in the state of São Paulo stages an annual campaign for prevention and early detection of oral cancer. This study sets out to evaluate the participatory planning of the teams at health facilities, seeking to list the difficulties encountered and strategies adopted over a five-year period (2006-2011) by analyzing the coverage of oral examinations for prevention and detection of disease. Strategies for tackling difficulties, issues of epidemiological coordination and surveillance raised by dentists, generated an increase in the coverage of tests performed in the population (> 60 years) from 21% in 2006 to 62% in 2011.

Association of breastfeeding, pacifier use, breathing pattern and malocclusions in preschoolers.

Objective: To evaluate the association of breastfeeding duration, pacifier use and nasal air flow with occlusal disorders among children.

Methods: This cross-sectional observational study included 138 children aged 4 and 5 years selected in all the daycare centers of the city of Campo Limpo Paulista, Brazil. Questionnaires were applied to mothers to identify total duration of exclusive breastfeeding and non-nutritive sucking.

[Assessment of educational actions on the oral health of adolescents within the Family Health Strategy].

Objective: to evaluate the actions of education on the oral health of adolescents within the scope of the Family Health Strategy.

Methodology: A questionnaire was applied and a clinical exam conducted evaluating biofilm and gingival inflammation in 80 adolescents before and after interventions. A qualitative study of the brushing technique was also performed on 15 adolescents in the sample.