Publications by authors named "Fabiana Boncimino"
Article Synopsis
- Skin cancer includes various types, with non-melanoma skin cancers (NMSCs) being the most prevalent globally, primarily caused by skin exposure to ultraviolet (UV) light.
- UV light causes genetic changes in skin cells that can promote cancer, especially when combined with a changed environment and immune suppression.
- Recent research has led to new treatments targeting specific pathways in advanced NMSC cases, but challenges like drug resistance and side effects remain, prompting ongoing studies for better therapies.
Unraveling the Functional Heterogeneity of Human Skin at Single-Cell Resolution.
Hematol Oncol Clin North Am
October 2024
The skin consists of several cell populations, including epithelial, immune, and stromal cells. Recently, there has been a significant increase in single-cell RNA-sequencing studies, contributing to the development of a consensus Human Skin Cell Atlas. The aim is to understand skin biology better and identify potential therapeutic targets.
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