Publications by authors named "Fabiana A Miranda-Camargo"
Cervical cancer remains persistently the second most common malignancies among women worldwide, responsible for 500,000 new cases annually. Only in Brazil, the estimate is for 18,430 new cases in 2011. Several types of molecular markers have been studied in carcinogenesis including proteins associated with apoptosis such as BAG-1 and PARP-1.
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- Laryngeal squamous cell carcinoma is a common cancer in Brazil, leading to about 3,000 deaths yearly, with HPV linked to its development.
- A study analyzed 63 laryngeal biopsies, assessing the expression of proteins p53, p27, and Mdm2 through immunohistochemistry while also checking for HPV presence.
- The results indicated that Mdm2 expression differs significantly between non-metastatic and metastatic carcinoma, implying its potential role in the cancer's invasiveness, while p53 and p27 showed no significant differences.