Publications by authors named "Fabian Thouillot"
Background: Dengue is a major public health concern in Reunion Island, marked by recurrent epidemics, including successive outbreaks of dengue virus serotypes 1 and 2 (DENV1 and DENV2) with over 70,000 cases confirmed since 2017.
Methodology/principal Findings: In this study, we used Oxford Nanopore NGS technology for sequencing virologically-confirmed samples and clinical isolates collected between 2012 and 2022 to investigate the molecular epidemiology and evolution of DENV in Reunion Island. Here, we generated and analyzed a total of 499 DENV1, 360 DENV2, and 18 DENV3 sequences.
Article Synopsis
- - Reunion Island has seen a resurgence of dengue outbreaks since 2018, with increasing severity and intensity, despite decades of low viral circulation.
- - A study conducted from 2018 to 2021 showed a rise in severe dengue cases and pediatric infections, with a notable shift in the dominant serotype from DENV2 to DENV1.
- - The findings suggest dengue is becoming endemic in the region, highlighting the need for health authorities to address the evolving public health implications associated with the disease.
Background: With the lengthening of life expectancy among HIV-positive subjects related to the use of highly active antiretroviral treatments, an increased risk of cancer has been described in industrialized countries. The question is to determine what occurs now and will happen in the future in the low income countries and particularly in sub-Saharan Africa where more than two-thirds of all HIV-positive people live in the world. The objective of our paper is to review the link between HIV and cancer in sub-Saharan Africa, putting it in perspective with what is already known in Western countries.
View Article and Find Full Text PDF