Publications by authors named "Fabian Garcia-Velasco"

Article Synopsis
  • * A 55-year-old male patient was diagnosed with HMSC, confirmed through various techniques, including immunohistochemistry (IHC) and genetic testing (PCR and RNA ISH), leading to successful treatment via surgery and radiotherapy.
  • * Whole exome sequencing (WES) identified 38 gene mutations and provided insights into possible personalized therapy targets, while no mutations were found to suggest drug response according to established databases.
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Background: Data about the results of transoral laser microsurgery (TLM) in elderly patients are limited.

Methods: A retrospective study of 72 consecutive cases of glottic carcinoma (63 pT1 and 9 pT2 cases) in elderly patients (≥70 years old, mean 76 years) treated with TLM was made. A systematic review of the literature was performed.

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Background: Recent studies support a role for human papillomavirus (HPV) in oropharyngeal squamous cell carcinomas (SCCs); however, the significance of HPV in non-oropharyngeal head and neck cancers is uncertain. The aim of this study was to determine the prevalence of HPV in a large cohort of laryngeal and hypopharyngeal SCCs in northern Spain.

Materials And Methods: Clinical records and paraffin-embedded tumor specimens of 124 consecutive patients surgically treated for laryngeal (62 cases) and hypopharyngeal (62 cases) SCCs between 2002 and 2007 were retrieved.

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