Publications by authors named "Fabia C S Soares"
This study has estimated the risk of Leishmania transmission via blood transfusion in one of the largest blood banks in Northeastern Brazil, where visceral leishmaniasis is endemic. Five hundred blood samples from donors were tested for circulating Leishmania spp. DNA by real-time PCR.
View Article and Find Full Text PDFDNA methylation is one of the mechanisms of epigenetic regulation and is observed in mammals to maintain a normal expression pattern of the genes. Aberrant profiles of DNA methylation have already been associated with cardiovascular diseases. We evaluated 190 patients with Acute Coronary Syndrome (ACS) and 75 patients without ACS (non-ACS).
View Article and Find Full Text PDFArticle Synopsis
- Conventional methods for identifying Leishmania species often rely on culturing parasites, which can fail and misrepresent the samples.
- A new technique called LSSP-PCR targets kDNA minicircles to provide accurate genotype identification directly from clinical samples or previously cultivated parasites.
- Although LSSP-PCR effectively differentiates between species and variants of Leishmania, the variability in profiles limits its effectiveness as a marker for species identification.