[Effects of octadecadienoic acid on proliferation and apoptosis of glioma cells and its mechanisms].

Objective: To study the effects of octadecadienoic acid (ODA) on the proliferation and apoptosis of glioma cells and its mechanisms.

Methods: Cultured human glioma cells (cell density 2×10 cells/L) were divided into solvent control group (DMSO, 30 μl/L), 5-FU group (10 mg/L) and octadecadienic acid groups (0.3, 0.

[Effects of the maca extract on the ultrastructures of mitochondria in the spinal nerve cell and exercise endurance].

Objective: To investigate the effects of maca extract on the ultrastructures of mitochondria in the spinal nerve cell and exercise endurance.

Methods: The Wistar rats were randomly divided into 5 groups, including the control group (no swimming), the swimming group (free swimming), and 3 treatment groups treated with the maca extract at the doses of 4.0, 5.

[Role of catecholamine hormone in heroin addicts].

Objective: To investigate the effects of catecholamine hormone on the blood and brain of heroin addicts.

Methods: Rats were divided into three groups and treated with the glucose (control group), the heroin (im) (heroin group), and the combination of the intramuscular injection of reserpine and heroin (reserpine group). Changes in the levels of the dopamine (DA), cAMP, and cGMP were detected by the radioimmunoassay (RIA) method in the blood and brain tissue.

Effects of a flavonoid extract from Cynomorium songaricum on the swimming endurance of rats.

The present study investigated the effects of a flavonoid extract from Cynomorium songaricum on the swimming endurance of rats by measuring changes of free radical scavenging enzymes, such as CuZn-SOD (copper, zinc-superoxide dismutase) and GSH-px (glutathione peroxidase), and body weights. Significant and dose-dependent antioxidant and anti-fatigue effects of flavonoids (rutin, catechin and isoquercitrin) on swimming rats were observed during 10 days of swimming exercise. After treatment with the flavonoid extract at doses of 0.

Isolation and characterization of methyl esters and derivatives from Euphorbia kansui (Euphorbiaceae) and their inhibitory effects on the human SGC-7901 cells.

Purpose: In this study, the inhibitory activity of the methyl esters and derivatives extracted from Euphorbia kansui (Euphorbiaceae) and their effect on apoptosis and cell cycle distribution in the human gastric cancer cell line (SGC-7901) were evaluated.

Methods: The inhibitory activity of the methyl esters and derivatives was evaluated by using trypan-blue, MTT (3-(4, 5-dimethyl thiazol-2yl) - 2, 5-diphenyltetrazolium bromide), and FCM (flow cytometry) assays. 5-fluorouracile (5-FU) was used for a positive control.