Objective: To observe the effect of manual acupuncture intervention on serotonin transporter (5-HTT), 5-HT 1 A receptor (5-HTR), norepinephrine (NE) alpha receptor 2 (NEαR) protein of brain tissues in rats with post-stroke depression (PSD).
Methods: Forty SD rats were randomly divided into normal group, model group, medication group and acupuncture group, with 10 rats in each. The PSD model was established by the combination of middle cerebral artery occlusion and chronic non- predictable mild stress.