Publications by authors named "Fa-Cai Wang"
Chronic kidney disease (CKD) is a clinical syndrome characterized by persistent renal function decline. Renal fibrosis is the main pathological process in CKD, but an effective treatment does not exist. Stratifin (SFN) is a highly-conserved, multi-function soluble acidic protein.
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- The outbreak of SARS-CoV-2 since late 2019 has led to a pneumonia epidemic affecting 236 countries, causing significant public health issues and multiple organ failures, particularly in critical patients.
- Previous coronaviruses, including SARS-CoV and MERS-CoV, have also shown a strong link to kidney damage in affected patients.
- This review focuses on summarizing the epidemiological and clinical features of these three pandemics, analyzing the mechanisms by which COVID-19 affects kidney health, and discussing the causes and prevention of secondary kidney diseases related to SARS-CoV-2.
Objective: To investigate the risk factors of medication nonadherence in patients with type 2 diabetes mellitus (T2DM) and to establish a risk nomogram model.
Methods: This retrospective study enrolled patients with T2DM, which were divided into two groups based on their scores on the Morisky Medication Adherence scale. Univariate and multivariate logistic regression analyses were used to screen for independent risk factors for medication nonadherence.
Induction profile of MANF/ARMET by cerebral ischemia and its implication for neuron protection.
J Cereb Blood Flow Metab
January 2010
Cerebral ischemia-induced accumulation of unfolded proteins in vulnerable neurons triggers endoplasmic reticulum (ER) stress. Arginine-rich, mutated in early stage tumors (ARMET) is an ER stress-inducible protein and upregulated in the early stage of cerebral ischemia. The purposes of this study were to investigate the characteristics and implications of ARMET expression induced by focal cerebral ischemia.
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