Wide Bandgap Semiconductors for Ultraviolet Photodetectors: Approaches, Applications, and Prospects.

Ultraviolet (UV) light, invisible to the human eye, possesses both benefits and risks. To harness its potential, UV photodetectors (PDs) have been engineered. These devices can convert UV photons into detectable signals, such as electrical impulses or visible light, enabling their application in diverse fields like environmental monitoring, healthcare, and aerospace.

A Dual-Functional Perovskite-Based Photodetector and Memristor for Visual Memory.

The imitation of human visual memory demands the multifunctional integration of light sensors similar to the eyes, and image memory, similar to the brain. Although humans have already implemented electronic devices with visual memory functions, these devices require a combination of various components and logical circuits. However, the combination of visual perception and high-performance information storage capabilities into a single device to achieve visual memory remains challenging.

Photoimaging with Color-Sensing Abilities by Tuning the Band Gap of a Single-Crystal Lead-Free Perovskite.

Photodetectors (PDs) composed of lead-free metal halide perovskites have been a shining topic in optoelectronics. However, it is debatable whether perovskites are an n-type or p-type semiconductor with a direct or indirect band gap. Furthermore, to date, little research has been conducted on lead-free metal halide perovskites with color-sensing abilities.

Enhanced Response Speed in 2D Perovskite Oxides-Based Photodetectors for UV Imaging through Surface/Interface Carrier-Transport Modulation.

The long-time decay process induced by the persistent photoconductivity (PPC) in metal oxides-based photodetectors (PDs) impedes our demands for high-speed photodetectors. 2D perovskite oxides, emerging candidates for future high-performance PDs, also suffer from the PPC effect. Here, by integrating 2D perovskite SrNbO (SNO) nanosheets and nitrogen-doped graphene quantum dots (NGQDs), a unique nanoscale heterojunction is designed to modulate surface/interface carrier transport for enhanced response speed.

Risk factors of in-hospital mortality in patients with pneumocystis pneumonia diagnosed by metagenomics next-generation sequencing.

Objectives: The metagenomic next-generation sequencing (mNGS) test is useful for rapid and accurate detection and identification of pathogenic microorganisms. The aim of the present study was to investigate the factors associated with in-hospital mortality in pneumocystis pneumonia (PCP) patients with mNGS-assisted diagnosis.

Methods: Our study enrolled 154 patients with mNGS-positive PCP from August 2018 to February 2022 at the First Affiliated Hospital of Zhengzhou University respectively.

An All-Organic Self-Powered Photodetector with Ultraflexible Dual-Polarity Output for Biosignal Detection.

Endowing photodetectors with mechanically flexibility and actual functionality are current research issues in developing optoelectronic devices. However, rigid metal-based or metal-oxide-based electrodes remain a block to the realization of ultraflexible electronics. Thus, an ultraflexible all-organic photodetector (all-OPD) is designed by innovatively introducing symmetrical organic electrodes PH1000/PH1000 to substitute the widely applied indium-doped tin oxide (ITO)/Ag electrodes.

[A prospective cohort study on the clinical value of pelvic peritoneal reconstruction in laparoscopic anterior resection for middle and low rectal cancer].

To investigate the safety and efficacy of pelvic peritoneal reconstruction and its effect on anal function in laparoscopy-assisted anterior resection of low and middle rectal cancer. A prospective cohort study was conducted. Consecutive patients with low and middle rectal cancer who underwent laparoscopy-assisted transabdominal anterior resection at Naval Military Medical University Changhai Hospital from February 2020 to February 2021 were enrolled.

[Molecular classification of colorectal carcinoma based on integration of gene expression profile and copy number variation].

Objective: To classify colorectal carcinoma (CRC) by TNM staging integrated with the gene expression profile and copy number variation (CNV).

Methods: Profile data of gene expression and CNV of CRC were downloaded from public database and processed with batch bias adjustment, quartile normalization, missing value estimation and feature filtration. The processed profiles of mRNA and CNV were introduced into the codes of Bayesian consensus clustering (BCC) method and were used to calculate the subclasses of CRC.

[Gene methylation in stool for the screening of colorectal cancer and pre-malignant lesions].

Objective: To evaluate association between DNA methylation of MAL, CDKN2A, and MGMT in stool and development of colorectal cancer, and to evaluate the screening value of these biomarkers in colorectal cancer and pre-malignant lesions.

Methods: Morning stool specimens were collected from 69 patients with colorectal cancer, 24 with colon adenoma, 19 with hyperplastic polyps, and 26 healthy controls. DNA was extracted and treated with bisulfite.

Patterns of lymph node metastasis are different in colon and rectal carcinomas.

Aim: To describe patterns of lymph node metastasis in invasive colon and rectal carcinomas.

Methods: Clinical data of 2340 patients with colorectal carcinoma (stage I to III) who received radical resection, was retrospectively reviewed. Of the 2340 patients, 1314 patients suffered from rectal carcinoma and 1026 from colon carcinoma.

[Lymph node metastasis and its risk factors in T1-2 staging invasive rectal carcinoma].

Objective: To investigate the lymph node metastasis and its risk factors in T1-2 staging invasive rectal carcinoma.

Methods: The data of 1116 patients with rectal cancer treated with total mesorectal excision (TME) technique from January 2000 to April 2009 was analyzed retrospectively. The clinicopathological factors analyzed included gender, age, primary symptom type, number of symptoms, duration of symptom, synchronous polyps, preoperative serum carcino-embryonic antigen level, preoperative serum CA19-9 level, the distance of tumor from the anal verge, tumor size, tumor morphological type, tumor circumferential extent, tumor differentiation and tumor T staging.

Could tumor characteristics identified by colonoscopy predict the locally advanced rectal carcinoma?

Background: Neoadjuvant chemoradiation is now considered the standard care for locally advanced rectal carcinoma (T3-4 or/and N1-2 lesions), but the accuracy of staging examinations including endorectal ultrasonography (ERUS) and MRI is far from excellent. In addition, the above staging equipment or professionals who perform the examinations may not be available in some hospitals, while preoperative colonoscopy and biopsy are usually obtainable in most hospitals. The objective of the present study was to investigate the clinical and pathological characteristics of locally advanced rectal carcinoma and identify candidates for neoadjuvant chemoradiation.

[Analysis on misdiagnosis of 271 patients with rectal cancer].

Objective: To investigate the common reasons for the misdiagnosis of rectal cancer.

Methods: A retrospective study was performed in 568 cases of rectal cancer in the Changhai Hospital from January 2007 to December 2008. Age at diagnosis, gender distribution, symptom, delay in diagnosis, TNM stage, and grade of differentiation were recorded and analyzed.