Publications by authors named "FUSARO A"

The European subtype of tick-borne encephalitis virus (TBEV-Eur; species , family ) was the only tick-borne flavivirus present in central Europe known to cause neurologic disease in humans and several animal species. Here, we report a tick-borne flavivirus isolated from Alpine chamois () with encephalitis and attached ticks, present over a wide area in the Alps. Cases were detected in 2017 in Salzburg, Austria, and 2023 in Lombardy and Piedmont, Italy.

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Between 21 September and 6 December 2024, 657 highly pathogenic avian influenza (HPAI) A(H5N1) and A(H5N5) virus detections were reported in domestic (341) and wild (316) birds across 27 countries in Europe. Many HPAI outbreaks in domestic birds were clustered in areas with high poultry density and characterised by secondary farm-to-farm spread. Waterfowl, particularly the mute swan, were primarily affected during this reporting period, with HPAI virus detections focused on south-eastern Europe.

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Article Synopsis
  • The study monitored the circulation of Influenza A virus (AIV) in wild ducks and birds in Lombardy from 2022-2024, analyzing samples collected from hunting and dead birds using real-time RT-PCR and whole genome sequencing.
  • Out of 3,497 hunted ducks, 184 tested positive for AIV, revealing 21 different subtypes, with H5N1 HPAIV being the most common during winter 2022-2023.
  • In surveys of dead wild birds, notably buzzards and gulls, two buzzards and one grey heron tested positive for H5N1, while gulls showed a significant increase in positivity from 0% in 2022 to 51%
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  • Between June 15 and September 20, 2024, Europe reported 75 cases of highly pathogenic avian influenza (HPAI) A(H5) and A(H7) in birds, mostly from wild populations along coastal areas, though overall cases were lower compared to previous years.
  • A new more transmissible strain, EA-2023-DT, was detected, and HPAI A(H7N5) emerged in a poultry establishment in Germany near the Netherlands.
  • In the US, there were 19 new human avian influenza cases, primarily linked to poultry exposure, with no evidence of human-to-human transmission, and the general public in the EU faces a low risk of infection.
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  • * Laboratory tests confirmed the presence of a low-pathogenicity avian influenza virus (LPAIV) subtype H6N1, affecting 15 premises in Northern Ireland and spreading to 13 in the Republic of Ireland and six in Great Britain.
  • * The outbreak resulted in the culling of over 2 million birds to control the spread, highlighting the significant economic consequences and the need for swift action during LPAIV outbreaks.
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Influenza A/H9 viruses circulate worldwide in wild and domestic avian species, continuing to evolve and posing a zoonotic risk. A substantial increase in human infections with A/H9N2 subtype avian influenza viruses (AIVs) and the emergence of novel reassortants carrying A/H9N2-origin internal genes has occurred in recent years. Different names have been used to describe the circulating and emerging A/H9 lineages.

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Between 16 March and 14 June 2024, 42 highly pathogenic avian influenza (HPAI) A(H5) virus detections were reported in domestic (15) and wild (27) birds across 13 countries in Europe. Although the overall number of detections in Europe has not been this low since the 2019-2020 epidemiological year, HPAI viruses continue to circulate at a very low level. Most detections in poultry were due to indirect contact with wild birds, but there was also secondary spread.

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  • Highly pathogenic avian influenza (HPAI A(H5N1)) caused high mortality rates among wild and domestic birds in Europe from 2020 to 2023, notably spreading to fur farms in Finland in July 2023.
  • The virus was detected in animals like silver and blue foxes, minks, and raccoon dogs, showing severe health issues and mutations that may help it adapt to mammalian hosts.
  • Close cooperation between animal and human health authorities was necessary to manage the outbreak and to address potential health impacts, as the virus was linked to mass bird die-offs and vulnerable farm biosecurity practices.
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Background: Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and early discharge. Fascia iliaca compartment block (FICB) has been recommended since it offers good pain control with a low risk of motor block. Pericapsular nerve group (PENG) block with lateral femoral cutaneous block (LFCN) has been proposed as an effective alternative to FICB that offers better pain control with a considerably lower risk of motor block.

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Between 2 December 2023 and 15 March 2024, highly pathogenic avian influenza (HPAI) A(H5) outbreaks were reported in domestic (227) and wild (414) birds across 26 countries in Europe. Compared to previous years, although still widespread, the overall number of HPAI virus detections in birds was significantly lower, among other reasons, possibly due to some level of flock immunity in previously affected wild bird species, resulting in reduced contamination of the environment, and a different composition of circulating A(H5N1) genotypes. Most HPAI outbreaks reported in poultry were primary outbreaks following the introduction of the virus by wild birds.

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Background: The introduction of multiple avian influenza virus (AIV) subtypes into Nigeria has resulted in several poultry outbreaks purportedly linked to trade and wild birds. The role of wild birds in perpetuating AIV in Nigeria was, therefore, elucidated.

Methods: A cross-sectional study was conducted among wild aquatic bird species at the Hadejia-Nguru wetlands in Northeastern Nigeria between March and April 2022.

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Between 2 September and 1 December 2023, highly pathogenic avian influenza (HPAI) A(H5) outbreaks were reported in domestic (88) and wild (175) birds across 23 countries in Europe. Compared to previous years, the increase in the number of HPAI virus detections in waterfowl has been delayed, possibly due to a later start of the autumn migration of several wild bird species. Common cranes were the most frequently affected species during this reporting period with mortality events being described in several European countries.

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The SARS-CoV-2 Delta variant of concern (VOC) was often associated with serious clinical course of the COVID-19 disease. Herein, we investigated the selective pressure, gene flow and evaluation on the frequencies of mutations causing amino acid substitutions in the Delta variant in three Italian regions. A total of 1500 SARS-CoV-2 Delta genomes, collected in Italy from April to October 2021 were investigated, including a subset of 596 from three Italian regions.

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Between 24 June and 1 September 2023, highly pathogenic avian influenza (HPAI) A(H5) outbreaks were reported in domestic (25) and wild (482) birds across 21 countries in Europe. Most of these outbreaks appeared to be clustered along coastlines with only few HPAI virus detections inland. In poultry, all HPAI outbreaks were primary and sporadic with most of them occurring in the United Kingdom.

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BackgroundOver a 3-week period in late June/early July 2023, Poland experienced an outbreak caused by highly pathogenic avian influenza (HPAI) A(H5N1) virus in cats.AimThis study aimed to characterise the identified virus and investigate possible sources of infection.MethodsWe performed next generation sequencing and phylogenetic analysis of detected viruses in cats.

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Between 29 April and 23 June 2023, highly pathogenic avian influenza (HPAI) A(H5N1) virus (clade 2.3.4.

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In 2021, amidst the COVID-19 pandemic and global food insecurity, the Nigerian poultry sector was exposed to the highly pathogenic avian influenza (HPAI) virus and its economic challenges. Between 2021 and 2022, HPAI caused 467 outbreaks reported in 31 of the 37 administrative regions in Nigeria. In this study, we characterized the genomes of 97 influenza A viruses of the subtypes H5N1, H5N2, and H5N8, which were identified in different agro-ecological zones and farms during the 2021-2022 epidemic.

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Between 2 March and 28 April 2023, highly pathogenic avian influenza (HPAI) A(H5Nx) virus, clade 2.3.4.

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Article Synopsis
  • Infectious bursal disease (IBD) is a viral disease affecting poultry, significantly impacting Nigeria's economy and food security, with outbreaks occurring even in vaccinated flocks.
  • Research on four near-complete IBDV genomes revealed specific conserved amino acid markers associated with very virulent strains and showed that these viruses cluster in a newly defined A3B5 group.
  • Unique mutations in the IBDV genomes indicate reassortant viruses, which could explain vaccination failures in Nigeria, highlighting the need for ongoing genome monitoring and effective vaccination strategies.
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We derive the analytical dispersion relation of a high-energy laser beam's backward stimulated Brillouin scattering (BSBS) in a hot plasma, that accounts both for the random phase plate (RPP) induced spatial shaping and its associated phase randomness. Indeed, phase plates are mandatory in large laser facilities where a precise control of the focal spot size is required. While the focal spot size is well controlled, such techniques produce small scale intensity variations that can trigger laser-plasma instabilities such as BSBS.

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Between 3 December 2022 and 1 March 2023 highly pathogenic avian influenza (HPAI) A(H5N1) virus, clade 2.3.4.

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Highly pathogenic avian influenza (HPAI) has caused widespread mortality in both wild and domestic birds in Europe during 2020-2022. Virus types H5N8 and H5N1 have dominated the epidemic. Isolated spill-over infections in mammals started to emerge as the epidemic continued.

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