Angiogenic nature of the "intravascular bronchioloalveolar tumor" of the lung: an electron microscopic study.

An intravascular bronchioloalveolar tumor of lung (IVBAT) was studied with electron microscopy. Based on ultrastructural evidence and information obtained from the literature, we propose the following: (1) IVBAT is a true pulmonary neoplasm with distinctive morphologic features; (2) it consists of cells with endothelial characteristics and is probably derived from multipotential mesenchymal reserve cells; (3) it is not related to the typical bronchioloalveolar tumor of lung; (4) a more appropriate designation for this unusual pulmonary neoplasm is "sclerosing angiogenic tumor."

Vertebral artery trauma: acute recognition and treatment.

Vertebral artery injury is uncommon and may be initially unrecognized. Sequelae of vertebral artery injury include arteriovenous fistulae and pseudoaneurysms that may appear months after injury. The incidence of the sequelae is unknown.

Gastric carcinoid tumor. Its occurrence with ossification and diffuse argyrophil-cell hyperplasia.

A case of two gastric carcinoid tumors accompanied by diffuse argyrophil-cell hyperplasia occurred in a 39-year-old woman. One of the gastric carcinoid tumors demonstrated stromal ossification. Diffuse argyrophil-cell hyperplasia accompanied by gastric carcinoid tumors has been reported previously.

Surgical correction of posttransplant renovascular hypertension.

The incidence of renovascular hypertension in the transplanted kidney is reported to range between 5 and 15%. A review of 391 consecutive renal transplant patients revealed 16 patients (5.4%) with hypertension secondary to partial obstruction of renal arterial blood flow.

Extracranial carotid artery injuries.

From December, 1975, to December, 1979, 54 carotid artery injuries have been treated by the Southwestern Medical School Department of Surgery. Seventy-eight percent were due to gunshot wounds, 20% were due to stab wounds, and 2% were secondary to blunt trauma. Thirty-three percent involved the internal carotid artery, and the external carotid artery was involved in 20%.

Intraoperative fine needle aspiration biopsy of thoracic lesions.

Forty-one intraoperative fine needle aspiration biopsies were performed on 35 patients during exploratory thoracotomy (33 patients) or mediastinoscopy (2 patients). Each biopsy was done with a 22 gauge needle. Smears were prepared at the operating table, air-dried, sent directly to the laboratory, stained, and interpreted immediately by the pathologist.

Acute and subacute pancreatitis. Role of surgery and endoscopic retrograde cholangiopancreatography.

Six of seven patients with acute pancreatitis who were intractable to prolonged medical therapy underwent successful endoscopic retrograde cholangiopancreatography (ERCP) followed by immediate operative therapy. All of these patients had surgically correctable lesions consistent with chronic pancreatitis. There was one associated mortality and no morbidity.

Concentrations of cephapirin sodium in plasma and gynecologic tissue after a single preoperative dose.

The penetration of cephapirin sodium into tissues that are commonly involved in gynecologic infections was studied after administration of a single i.v. dose of 1 g of cephapirin to about 15 patients to undergo gynecologic surgery.

Endothelial response to venous injury.

This investigation characterized venous endothelial healing after surgical manipulation. Procedures were performed on jugular and femoral veins in 21 mongrel dogs without systemic anticoagulation. Veins were harvested at varying intervals and vessel structure evaluated with light, transmission, and scanning electron microscopy.

Appendicitis and aortofemoral graft infection.

A 59-year-old man who underwent successful aortofemoral bypass had acute appendicitis at an indeterminate time in the postoperative period. Thirteen months later, a pulsatile groin mass developed. After a complicated course, it was found that infection from appendicitis had extended to the body of the graft.

Hypotension and hypertension as consequences of baroreceptor dysfunction following carotid endarterectomy.

Arterial pressure regulation is often labile following carotid endarterectomy. Hemodynamic data from 100 consecutive endarterectomies allowed definition of three distinct postoperative blood pressure responses. A hypotensive response (group I) affected 28 patients in whom mean arterial pressure decreased from 168 +/- 29/90 +/- 15 mm Hg before operation to 110 +/- 21/68 +/- 16 mm Hg after operation (P less than 0.

Vertebral arteriovenous fistula associated with an anomalous arterial vessel.

The widespread use of angiography in patients sustaining vascular trauma has demonstrated an increased incidence in vertebral artery injuries. With the improvement in peripheral vascular techniques and the utilization of extended exposure of the vertebral artery, aggressive therapy now is generally advocated. While new concepts continue to evolve, it becomes important to report anatomical variants that are not commonly recognized.

Differing actions of nitroprusside and D-600 on tension and 45Ca fluxes in canine renal arteries.

Administration of nitroprusside (NP) subsequent to induction of contraction in canine renal arterial strips with norepinephrine (NE) yielded a dose-dependent relaxation and with 80 mM potassium (KCl) yielded only a small degree of relaxation. The effect elicited with 0.1 mM NP was significantly greater for responses obtained with NE (68%) than for those with KCl (12%).

Effects of norepinephrine, dopamine and potassium on tension and 45Ca fluxes in canine and rabbit renal arteries.

The action and interactions of three vasoconstrictors, norepinephrine (NE), dopamine (DA) and elevated potassium ion (K+) on contractile responses and associated 45Ca movements were investigated in isolated rabbit and canine renal arteries (RA). Dose-response curves indicate that NE is 39 times more potent than DA in canine RA and 122 times more potent in rabbit RA. Prior exposure to 80 mM K+ did not prevent contractile responses to NE or DA but, conversely, K+ -induced responses did not occur after exposure to NE or DA.

Ultrastructure of medial smooth muscle and myofibroblasts in human arterial dysplasia.

Ultrastructural characteristics of 20 dysplastic human renal arteries were documented. Loss of smooth muscle with collection of fibrous connective tissue predominated in medical fibrodysplasia, whereas excessive accumulations of elastic fibrils typified perimedial dysplasia. Myofibroblasts were a unique feature of both forms of arterial dysplasia.

Portal hypertension following renal transplantation.

Portal hypertension and variceal hemorrhage may be found in the renal transplant patient with chronic liver disease. The development of portal hypertension was found to occur after long-term graft survival without significant rejection. The development of positive cytomegalic virus and negative hepatitis-associated antigen appeared to be common.