Speech as a Graph: Developmental Perspectives on the Organization of Spoken Language.

Language has been used as a privileged window to investigate mental processes. More recently, descriptions of psychopathological symptoms have been analyzed with the help of natural language processing tools. An example is the study of speech organization using graph theoretical approaches that began approximately 10 years ago.

Graph structure analysis of speech production among second language learners of Spanish and Chinese.

Language experience shapes the gradual maturation of speech production in both native (L1) and second (L2) languages. Structural aspects like the connectedness of spontaneous narratives reveal this maturation progress in L1 acquisition and, as it does not rely on semantics, it could also reveal structural pattern changes during L2 acquisition. The current study tested whether L2 lexical retrieval associated with vocabulary knowledge could impact the global connectedness of narratives during the initial stages of L2 acquisition.

Psychological inflexibility in overweight and obese people from the perspective of acceptance and commitment therapy (ACT).

Purpose: To identify the psychological inflexibility (PI) processes (experiential avoidance, cognitive fusion, poor contact with the present moment, unclear personal values and lack of commitment to action) associated with body mass index (BMI), depression, anxiety and stress symptoms and binge eating in overweight and obese people by drawing on the acceptance and commitment therapy (ACT) framework.

Methods: A cross-sectional study of 243 people with a BMI of at least 25 and aged from 18 to 60 years old. The following instruments were used: Acceptance and Action Questionnaire II (AAQ-II), Acceptance and Action Questionnaire-Weight (AAQ-W), Valued Living Questionnaire (VLQ), Cognitive Fusion Questionnaire (CFQ-7), Cognitive Fusion Questionnaire-Body Image (CFQ-BI), Mindful Eating Questionnaire (MEQ), Binge Eating Scale (BES) and Depression, Anxiety and Stress Scale (DASS-21).

Estradiol cypionate aided treatment for experimentally induced ascending placentitis in mares.

The overall goal of this study was to assess the efficacy of various therapeutic combinations of estradiol cypionate (ECP, a long-acting estrogen) and altrenogest (ALT, a long-acting progestin) in addition to basic treatment for placentitis with trimethoprim-sulfamethoxazole (TMS) and flunixin meglumine (FM). Specific outcomes measured in this experiment were (i) time from induction of bacterial placentitis to delivery, and foal parameters (high-risk, survival, and birth weight); and (ii) serum steroid concentrations (progesterone, 17α-hydroxyprogesterone, 17β-estradiol, and cortisol) in response to treatment. Pregnant mares (∼300 days gestation, n = 46) were randomly assigned into healthy mares (control group, CONT, n = 8) and mares with experimentally induced ascending placentitis (n = 38).

Fabricating complete dentures with CAD/CAM technology.

Conventional complete denture prosthetics require several appointments to register the maxillomandibular relationship and evaluate the esthetics. The fabrication of milled complete dental prostheses with digital scanning technology may decrease the number of appointments. The step-by-step method necessary to obtain impressions, maxillomandibular relation records, and anterior tooth position with an anatomic measuring device is described.

Mechanical and biocompatible characterization of a cross-linked collagen-hyaluronic acid wound dressing.

Collagen scaffolds have been widely employed as a dermal equivalent to induce fibroblast infiltrations and dermal regeneration in the treatment of chronic wounds and diabetic foot ulcers. Cross-linking methods have been developed to address the disadvantages of the rapid degradation associated with collagen-based scaffolds. To eliminate the potential drawbacks associated with glutaraldehyde cross-linking, methods using a water soluble carbodiimide have been developed.

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This study investigates the phonological acquisition of Brazilian Portuguese (BP) by a group of 24 bimodal bilingual hearing children, who have unrestricted access to Brazilian Sign Language (Libras), and a group of 6 deaf children, who use cochlear implants (CI), with restricted or unrestricted access to Libras. The children's phonological system of BP was assessed through the Naming Task (Part A) of the ABFW - Children Language Test (ANDRADE et al. 2004).

Second language processing shows increased native-like neural responses after months of no exposure.

Although learning a second language (L2) as an adult is notoriously difficult, research has shown that adults can indeed attain native language-like brain processing and high proficiency levels. However, it is important to then retain what has been attained, even in the absence of continued exposure to the L2--particularly since periods of minimal or no L2 exposure are common. This event-related potential (ERP) study of an artificial language tested performance and neural processing following a substantial period of no exposure.

Nerve growth factor and brain-derived neurotrophic factor but not granulocyte colony-stimulating factor, nimodipine and dizocilpine, require ATP for neuroprotective activity after oxygen-glucose deprivation of primary neurons.

In previous work, we have demonstrated by radiolabeling, mass spectrometry and site-directed mutagenesis that nerve growth factor (NGF) as well as brain-derived neurotrophic factor (BDNF) and fibroblast growth factor 2 (FGF2) are capable of ATP-binding and that this binding appears to be essential for their neuroprotective activity. In this study, we attempted to shed some light on the question whether ATP is a general prerequisite for neuroprotection. Therefore, we used the non-ATP-binding granulocyte colony-stimulating factor (GCSF), the calcium antagonist nimodipine and the NMDA antagonist dizocilpine to find out whether they need ATP for neuroprotection comparable to NGF and BDNF.

Interaction of clodronate with fibroblast growth factor 2 reduces FGF2-activity in endothelial cells.

Stabilization of fibroblast growth factors from heat denaturation and proteolytic digestion by bound heparin and heparan sulphate proteoglycans is known for more than 20 years. Furthermore, ATP-binding to FGF2 also leads to stabilization of this growth factor as discovered recently. The physiological importance of this protection is not yet clear but has become the focal point of interest.

Absolute brightness of fluorescent microspheres.

The absolute brightness of fluorescent particles, such as dye-containing nano- and microspheres or quantum dots, is a critical design parameter for many applications relying on fluorescence detection. The absolute brightness, defined as the ratio of radiant intensity of emission to illumination intensity of excitation, of nile-red fluorescent microspheres with a 1 micrometre diameter is measured to be 4.2 +/- 1 x 10(-16) m(2)/sr, and the implications for the design of kinesin motor protein-powered "smart dust" devices and the remote detection of fluorescence are discussed.

A novel technique using a coded healing abutment for the fabrication of a CAD/CAM titanium abutment for an implant-supported restoration.

This article describes the use of CAD/CAM titanium abutments for restoring dental implants. This new system incorporates both advantages of modern technology and a simplified impression technique with a coded healing abutment.

Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoring.

Synaptic plasticity and memory formation involve remodeling of the postsynaptic cytoskeleton, a process that is in part based on both local translation of dendritic mRNAs and synaptic recruitment of newly synthesized proteins. The postsynaptic component Dendrin that is encoded by a dendritically localized mRNA is thought to modulate the structure of the synaptic cytoskeleton. However, molecular mechanisms that control extrasomatic Dendrin mRNA transport and postsynaptic protein recruitment are unknown.

Indications for splinting implant restorations.

Purpose: The purpose of this article was to review the literature concerning the need to splint implants together when restoring them with a provisional restoration immediately after implant placement.

Methods: The literature is reviewed concerning the rationale for splinting teeth and reports concerning the efficacy of splinting implants together. Based on this team's experience with a prospective series of consecutive 2 to 5 unit provisionalization cases, guidelines are included with case examples for understanding the technique.

A prosthetic solution to restoring the edentulous mandible with limited interarch space using an implant-tissue-supported overdenture: a clinical report.

An implant-retained overdenture retained with 2 implants placed in the anterior edentulous mandible is a simple and predictable treatment option. The fabrication and use of this prosthesis requires satisfactory interarch space for adequate denture base thickness and esthetics. This clinical report describes the use of low-profile attachments for this overdenture design to solve the problem of limited interarch space.

Immediate loading of dental implants in the edentulous mandible.

Background: The authors review the literature regarding immediate implant loading in the anterior edentulous mandible, demonstrate the technique they currently use, review preliminary results and present an illustrative case.

Materials And Methods: The authors conducted a literature search using PUBMED and Ovid databases. They considered for review 31 articles in English from 1969 to 2003 that pertained to immediate loading of the anterior mandible.

In vitro fracture strength of teeth restored with different all-ceramic crown systems.

Statement Of Problem: There is insufficient knowledge of the strength of all-ceramic crowns bonded to natural teeth to warrant the use of all-ceramic crowns in place of metal-ceramic crowns.

Purpose: The purpose of this study was to evaluate and compare fracture resistance of crowns made of 3 different types of 2 all-ceramic crown systems-0.4-mm and 0.

A multidisciplinary approach to restoring an acquired palatal defect using distraction osteogenesis: a clinical report.

Prosthetic and surgical procedures can be applied to rehabilitate acquired palatal defects. Distraction osteogenesis may be used to narrow the defect to facilitate bone and soft tissue closure. This clinical report describes a multidisciplinary approach to the closure of a palatal defect with distraction osteogenesis, comprehensive orthodontic treatment, surgical soft tissue flap reconstruction of the residual soft tissue defect, implant placement in the newly created edentulous ridge, and restoration with an implant-supported prosthesis.

Single tooth immediate provisional restoration of dental implants: technique and early results.

Purpose: Patients desire efficient restoration of missing teeth. Immediate provisionalization of implants at the time of placement can provide the patient with a tooth-like restoration. Our hypothesis is that preoperative fabrication of the implant abutment and provisional restoration can provide successful immediate provisionalization of implants, if specific diagnostic criteria are used for patient selection.

Immediate loading of the edentulous mandible: delivery of the final restoration or a provisional restoration--which method to use?

Purpose: Edentulous patients desire restoration of their chewing ability as soon as possible after placement of dental implants. The purpose of this article is to provide clinicians with evidence that immediate loading of implants placed into the anterior mandible can predictably provide the patient with early functional rehabilitation. Two methods are presented that illustrate delivery of the final restoration or a provisional implant-borne prosthesis immediately after implant placement.

The IPM Wheat Model--results of a three-year study in North Rhine-Westphalia, Lower Saxony and Schleswig-Holstein.

Under the primary utilisation of phytosanitary production factors such as selection of variety, crop rotation and N fertilisation according to plant requirements, the IPM Wheat Model comprises the elements diagnosis (qualitative = type of pathogen, quantitative = disease severity), scientifically grounded treatment thresholds which, as critical values in pathogen development, can be applied to define the optimum time of fungicide application, and pathogen-specific effective fungicides and application amounts. This leads to the location and year-specific optimised control of the pathogen and of the associated yield performance. After several years of development in Bavaria (from 1985 on) and Schleswig-Holstein (1993-1999), the model was tested as part of a project involving the Universities of Bonn and Kiel and the plant protection services of the German states of Lower Saxony, North Rhine-Westphalia and Schleswig-Holstein in a three-year study (1999-2001) in interregional locations (usually nine per state) with the winter wheat variety Ritmo (interregional indicator variety) and a further variety of regional importance in different variations (untreated control, three to four times growth stage-oriented variants for the determination of the absolute damage potential, IPM-variant).

Immediate implant placement and provisionalization using implants with an internal connection.

Single-tooth implant restoration has evolved from traditional two-stage surgical procedures to techniques that allow implant placement and provisionalization immediately following tooth extraction. Restorative success using an immediately provisionalized implant system is based upon adherence to several clinical and biological parameters. This article will discuss the clinical and restorative considerations that must be addressed when immediately loading single-tooth implants.

The evolution of external and internal implant/abutment connections.

The indications for implant dentistry continue to increase, enabling the restoration of partially and totally edentulous patients with greater success and predictability. Recent goals for implant dentistry include simplifying the involved procedures, reducing the duration of therapy for the patient and clinician, and enabling the use of conventional prosthodontic techniques for implant-supported restorations. This article reviews key developments in implantology and highlights the various design characteristics of internal abutment connection implants, demonstrating their clinical application in a detailed case presentation.