Publications by authors named "F van den Berg"

Article Synopsis
  • The study investigates challenges in delivering nanoparticle-based drugs to tumors, focusing on the inconsistent success of the enhanced permeability and retention (EPR) effect.
  • It introduces a technique using multiparametric dynamic contrast-enhanced ultrasound (CEUS) with nanoscale contrast agents to noninvasively analyze tumor microenvironment features and predict the distribution and effectiveness of doxorubicin-laden liposomes.
  • Results indicate that CEUS parameters, like area under the curve and decorrelation time, can accurately differentiate between tumors with varying vascular permeability, potentially serving as biomarkers for treatment responsiveness to nanoparticle therapies.
View Article and Find Full Text PDF

Contrast-enhanced ultrasound is currently used worldwide with clinical indications in cardiology and radiology, and it continues to evolve and develop through innovative technological advancements. Clinically utilized contrast agents for ultrasound consist of hydrophobic gas microbubbles stabilized with a biocompatible shell. These agents are used commonly in echocardiography, with emerging applications in cancer diagnosis and therapy.

View Article and Find Full Text PDF

Sustainable fisheries management is important for the continued harvest of the world's marine resources, especially as they are increasingly challenged by a range of climatic and anthropogenic factors. One of the pillars of sustainable fisheries management is the accurate identification of the biological units, i.e.

View Article and Find Full Text PDF

Background: Zymoseptoria tritici causes Septoria tritici blotch (STB), which is the biggest threat to wheat in the UK. Azole fungicides have been used since the 1980s to control STB, but resistance to these chemicals is now widespread. The main resistance mechanism is based on the accumulation of CYP51 mutations, with 33 mutations reported.

View Article and Find Full Text PDF

Raiding seals pose a big problem to gillnet fishers in areas with high seal abundances. As moving to active gears could be a potential solution for that problem, one gear of particular interest in areas with relatively flat sea bed structure is the so-called "MiniSeine" - a demersal seine that is reduced in size so it can be operated from small vessels. Besides its ability to catch most of the species targeted by gillnet fishers, it offers various advantages compared to other active gears.

View Article and Find Full Text PDF