Access of transgender people and transvestites to pre-exposure prophylaxis for HIV in Brazil: a descriptive study, 2018-2023.

Objectives: To analyze access to pre-exposure prophylaxis (PrEP) for HIV in Brazil, comparing transgender and cisgender populations.

Methods: This was a descriptive study using data from the Medication Logistics Control System (Sistema de Controle Logístico de Medicamentos - SICLOM), related to the monitoring of PrEP between January 2018 and December 2023.

Results: During the period analyzed, 149,022 people initiated PrEP, of whom 139,423 (94%) were cisgender and 9,599 (6%) were transgender.

Surface Roughness and Color Stability of Conventional and Bulk-Fill Resin Composite with S-PRG Fillers After Coffee Exposure: An in-vitro Study.

Objective: This study aimed to evaluate the in vitro effects of coffee exposure on the color and roughness of conventional and bulk-fill resin composites, with and without surface pre-reacted glass-ionomer (S-PRG) filler.

Methodology: Forty-eight cylindrical samples (Ø6 mm × 2 mm) were prepared and categorized as follows (n = 12 per group): conventional nano-hybrid (Tetric N-Ceram, Ivoclar); nano-hybrid with S-PRG filler (Beautifil II, Shofu); bulk-fill (Tetric N-Ceram Bulk Fill, Ivoclar); and bulk-fill with S-PRG filler (Beautifil Bulk Restorative, Shofu). The samples were assessed for surface roughness (Ra, μm), color coordinates (CIE Lb), and overall color change (ΔE, ΔE).

Coating Agents for Resin Composites: Effect on Color Stability, Roughness, and Surface Micromorphology Subjected to Brushing Wear.

This study evaluated the influence of six resin composite coating agents on color stability and surface roughness after toothbrushing abrasion. Discs (Ø6 mm x 2 mm) of nanofilled resin composite (Filtek Z350XT) were prepared for application of coating agents (n=10): control (absence), two surface sealants (PermaSeal and BisCover LV), two adhesive systems (Scotchbond Multi-Purpose Adhesive/3M Oral Care and Single Bond Universal), and two modeling liquids (Modeling Resin and Composite Wetting Resin). CIELab*, WID, and color change (ΔEab, ΔE00, and ΔWID) were analyzed at baseline, after finishing and polishing, after application of coating agents, after coffee staining (simulating 30 days and one year of staining), and after toothbrushing abrasion.

Titanium dioxide nanotubes incorporated into conventional glass ionomer cement alter the biological behavior of pre-odontoblastic cells.

The objective was to address the repercussion of adding titanium dioxide nanotubes (TiO-nt) into high-viscosity conventional glass ionomer cement (GIC) on the biological properties of pre-odontoblastic cells (MDPC-23) challenged by lipopolysaccharides (LPS - 2 μg/mL). TiO-nt was added to Ketac Molar EasyMix at 3, 5, 7 %, whereas unblended GIC served as control. Analyses included proliferation (n=6; 24, 48, 72 h), metabolism (MTT; n=6; 24, 48, 72 h); morphology laser microscopy (n=3; 24, 48, 72 h); proteome assessments IL-1β, IL-6, IL-10, VEGF, TNF-α (n=3; 12, 18 h); mRNA levels (RT-PCR) of Il-1β, Il-6, Il-10, VEGF, TNF-α (n=3; 12, 18 h) and DSPP (n=3; 24, 72, 120 h).

Effect of diode laser irradiation on bond strength of resin cements to high-translucent zirconia.

Background: Treatment of acid-resistance high-translucent zirconia prior to luting procedures is usually carried out with sandblasting. Considering that this process could lead to the formation of cracks on the zirconia surface, laser irradiation became an alternative to sandblasting. The effect of diode laser, however, was never investigated under this context.