Dual optical elastography detects -induced alterations in the biomechanical properties of skin scaffolds.

Significance: The skin's mechanical properties are tightly regulated. Various pathologies can affect skin stiffness, and understanding these changes is a focus in tissue engineering. skin scaffolds are a robust platform for evaluating the effects of various genetic and molecular interactions on the skin.

Revealing regional variations in scleral shear modulus in a rabbit eye model using multi-directional ultrasound optical coherence elastography.

The mechanical properties of the sclera play a critical role in supporting the ocular structure and maintaining its shape. However, non-invasive measurements to quantify scleral biomechanics remain challenging. Recently introduced multi-directional optical coherence elastography (OCE) combined with an air-coupled ultrasound transducer for excitation of elastic surface waves was used to estimate phase speed and shear modulus in ex vivo rabbit globes (n = 7).

Optical coherence elastography measures the biomechanical properties of the porcine cornea after LASIK.

Significance: The biomechanical impact of refractive surgery has long been an area of investigation. Changes to the cornea structure cause alterations to its mechanical integrity, but few studies have examined its specific mechanical impact.

Aim: To quantify how the biomechanical properties of the cornea are altered by laser assisted keratomileusis (LASIK) using optical coherence elastography (OCE) in porcine corneas.

Estimation of the full shape of the crystalline lens from OCT: validation using stretched donor lenses.

Quantifying human crystalline lens geometry as a function of age and accommodation is important for improved cataract and presbyopia treatments. In previous works we presented as a basis of 3-D functions to represent the full shape of the crystalline lens . Also, we presented the application of to estimate the full shape of the lens from 3-D optical coherence tomography (OCT) images, where only the central part of the lens -visible through the pupil- is available.

Multiple Optical Elastography Techniques Reveal the Regulation of Corneal Stiffness by Collagen XII.

Purpose: Collagen XII plays a role in regulating the structure and mechanical properties of the cornea. In this work, several optical elastography techniques were used to investigate the effect of collagen XII deficiency on the stiffness of the murine cornea.

Methods: A three-prong optical elastography approach was used to investigate the mechanical properties of the cornea.