Publications by authors named "F Zaragoza"
Article Synopsis
- The history of pharmacology in Spain began gaining independence as a science in Europe with the establishment of university chairs, notable with Osswald Shmiedeberg’s appointment in 1872 in Germany, which influenced Spanish pharmacology.
- Teófilo Hernando emerged as a significant figure in early 20th century Spain, pioneering the integration of modern pharmacology into medical education and directly training various pharmacologists, fostering growth in this field across Spanish universities.
- Despite interruptions from historical events like the Spanish Civil War and World Wars, the discipline evolved, leading to the formation of the "Sociedad Española de Farmacología" in 1972, as the impact of Hernando's students continued to expand pharmacological research and education
Herbal medicines (HMs) have been traditionally used for the prophylaxis/treatment of cardiovascular diseases (CVDs). Their use is steadily increasing and many patients with CVDs often combine HMs with prescribed cardiovascular medications. Interestingly, up to 70% of patients do not notify cardiologists/physicians the use of HMs and up to 90% of cardiologists/physicians may not routinely inquire them about the use of HMs.
View Article and Find Full Text PDFAn increasing number of drugs that consist of a therapeutic peptide or protein linked to an albumin-binding structure are being approved. In this perspective, the pharmacokinetic data of currently marketed drugs of this type will be presented. Acylation with fatty acids or fatty α,ω-dicarboxylic acids has been used successfully to prepare long-acting analogs of insulin, GLP-1, and other peptides but not of larger proteins.
View Article and Find Full Text PDFFlavonoids are compounds with a benzopyranic structure that exhibits multiple pharmacological activities. They are known for their venotonic activity, but their mechanism of action remains unclear. It is thought that, as this mechanism is mediated by prostaglandins, these compounds may interfere with the arachidonic acid (AA) cascade.
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