A novel tool for predicting the dose distribution of non-sealed Re (Rhenium) resin in non-melanoma skin cancers (NMSC) patients.

Background: High-dose rate brachytherapy using a non-sealed Rhenium resin ( Re) is a recently approved treatment option for non-melanoma skin cancer (NMSC). The treatment goal is to deliver a personalized absorbed dose to the deepest point of neoplastic infiltration corresponding to the minimal target dose. The treatment consists of the application of a Re-based resin over a plastic foil placed on the target skin surface.

A novel figure of merit to investigate Ga PET/CT image quality based on patient weight and lesion size using Q.Clear reconstruction algorithm: A phantom study.

Introduction: Q.Clear is a Bayesian penalised-likelihood algorithm that uses a β-value for positron emission tomography(PET)/computed tomography(CT) image reconstruction(IR). Our study proposes a novel figure of merit, named CRBV, to compare the Q.

A novel tool for motion-related dose inaccuracies reduction in Tc-MAA SPECT/CT images for SIRT planning.

Introduction: In Selective Internal Radiation Therapy (SIRT), Y is administered to primary/secondary hepatic lesions. An accurate pre-treatment planning using Tc-MAA SPECT/CT allows the assessment of its feasibility and of the activity to be injected. Unfortunately, SPECT/CT suffers from patient-specific respiratory motion which causes artifacts and absorbed dose inaccuracies.