Publications by authors named "F X Rius"

Background: Adherence is critical in patients with Alzheimer's disease (AD) in order to achieve optimal benefit from therapy. However, patient compliance with the treatment remains a challenge.

Objective: To evaluate, in a real-world clinical setting, caregiver preference and treatment compliance with twice-weekly versus daily transdermal rivastigmine patch in mild-to-moderate AD.

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Introduction: Sleep Apnea-Hypopnea Syndrome (SAHS) is a common sleep disorder influenced by factors like age, gender, and obesity. The Mediterranean Diet (MedDiet) and physical activity have shown health benefits in lung diseases, but their effects on SAHS remain underexplored.

Methods: In a cross-sectional analysis of 678 middle-aged individuals with low-to-moderate cardiovascular risk from the ILERVAS cohort, we assessed adherence to the MedDiet and physical activity levels using validated tools.

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Purpose: To present a descriptive analysis of pediatric craniopharyngiomas (PedCPG) treated in various Spanish hospitals, defining factors related to recurrence and performing a critical analysis of the results.

Methods: We undertook a multicenter retrospective review of PedCPG treated between 2000 and 2017. Data collected included epidemiological variables, clinical and radiological characteristics, goal of first surgery, rate of recurrence and its approach, adjuvant treatment, complications and permanent morbidity.

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To evaluate the efficacy, safety and satisfaction of the closed-loop system Accu-Chek Insight with Diabeloop™ (DBLG1™) in adults with type 1 diabetes (T1D) in real-world conditions. Patients with T1D using DBLG1 for at least 3 months were included. Glucometric parameters were analyzed at baseline, 1, 2, and 3 months after starting DBLG1.

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Article Synopsis
  • The study investigates the epigenetic changes in melanoma progression using a four-stage cell line model, examining how CpG methylation varies across different stages: from non-tumorigenic melanocytes to metastatic melanoma cells.
  • Researchers identified specific gene promoters that are hypo- and hypermethylated, which characterize distinct malignancy and metastasis signatures, totaling 540 hypo- and 37 hypermethylated promoters for malignancy, and 646 hypo- and 520 hypermethylated promoters for metastasis.
  • The findings suggest that specific CpGs could serve as potential markers for predicting poor survival in melanoma patients, as they showed a correlation between DNA methylation and transcriptional levels in key genes linked to melanoma prognosis.
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