Obstructive sleep apnea among obese patients with type 2 diabetes.

Objective: To assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among obese patients with type 2 diabetes.

Research Design And Methods: Unattended polysomnography was performed in 306 participants.

Results: Over 86% of participants had OSA with an apnea-hypopnea index (AHI) >or=5 events/h.

The insulin resistance syndrome and coronary artery disease.

Insulin resistance is an increasingly common metabolic abnormality characterized by an impaired physiological response to insulin. The constellation of insulin resistance and several other metabolic and vascular disorders is known as the insulin resistance syndrome. The characteristic features of the insulin resistance syndrome include central obesity, hypertension, dyslipidemia, glucose intolerance and specific abnormalities of both endothelial cell and vascular function.