Publications by authors named "F X Castellanos-Juarez"
Prevalence and Classification of C-Shaped Canal and Radix in Mandibular Molars Using Cone-Beam Computed Tomography on Mexican Population.
Dent J (Basel)
July 2024
Article Synopsis
- The study examines the complexity of teeth anatomy, especially focusing on C-shaped canals and radix entomolaris, which impact the effectiveness of root canal treatments.
- Using cone-beam computed tomography (CBCT), researchers identified the prevalence and types of these anatomical variations in a sample of 2173 teeth from a Mexican population.
- Results showed that C-shaped canals were more common in second mandibular molars, with a significant gender difference in prevalence, highlighting the importance of understanding these variations for improving endodontic treatment success rates.
Article Synopsis
- Parkinson's disease (PD) is a neurodegenerative disorder associated with abnormal protein clumping and faulty protein regulation, prompting this study to analyze gene expression in a Mexican-Mestizo PD group compared to healthy individuals.
- The research involved 87 PD patients and 87 controls, revealing significant downregulation of specific genes in the PD group, which correlates with the disease's presence.
- A newly developed gene expression model based on these findings shows potential for accurately diagnosing early-stage PD, highlighting a notable connection between reduced gene expression and the condition in the studied population.
Background: Among the Toll-like receptors (TLR) that are dependent of myeloid response protein (MyD88), the TLR4 and TLR2 are directly associated with low-grade chronic inflammation; however, they are not been investigated in subjects with metabolically healthy obesity (MHO). Thus, the objective of this study was to determine the association between the expression of TLR4, TLR2, and MyD88 with low-grade chronic inflammation in individuals with MHO.
Methods And Results: Men and women with obesity aged 20 to 55 years were enrolled in a cross-sectional study.
Clinical criteria diagnose Parkinson's disease (PD), therefore, it is crucial to find biological elements that could support diagnosis or even act as prognostic tools of PD. The SNCA gene codifies a protein called α - synuclein; several studies associate genetic and biochemical factors of SNCA with PD, including transcript and plasmatic protein levels, however, contradictory evidence indicates inconclusive results. We aim to compare SNCA mRNA expression, plasmatic α-syn protein and rs356219 SNP between PD cases and a control group, and to identify a potential biomarker in Mexican mestizos', focusing on these three components determined in blood.
View Article and Find Full Text PDFObjective: To determine the seroprevalence of immunoglobulin (Ig)G and IgM antibodies and its association with the characteristics of the study population from the northern Mexican city of Durango, Mexico.
Methods: Through a cross-sectional study design, inhabitants of Durango City, Mexico were surveyed between June 2018 and November 2018. Serum samples from the subjects were analysed for anti- IgG and IgM antibodies using commercially available enzyme-linked immunosorbent assays.