Microfocused Ultrasound With Visualization Induces Remodeling of Collagen and Elastin Within the Skin.

Purpose: Microfocused ultrasound with real-time visualization (MFU-V) is often used for noninvasive skin lifting, by precisely targeting dermal and subcutaneous tissues to create thermal coagulation points (TCPs). These TCPs denature collagen and initiate a transient inflammatory response, ultimately attracting dermal fibroblasts and inducing efficient neocollagenesis and extracellular matrix (ECM) remodeling, yielding to MFU-V's desired skin-lifting effects. The current study investigates MFU-V's underlying mode of action based on the histological progression of TCPs in the skin, providing new insight into the technology's regenerative effect.

Myotonometry and extended field-of-view ultrasound imaging allow reliable quantification of patellar tendon stiffness and length at rest and during maximal load, whereas several restrictions exist for the Achilles tendon.

Introduction: Stiffness and length are well-established tendon parameters in sports and medicine. Myotonometry and ultrasound imaging are the commonly used methods to quantify these parameters. However, further studies are needed to clarify the reliability of these methods, especially when assessing maximally loaded tendons and when conducted by different experienced investigators.

Effects of Digital Physical Health Exercises on Musculoskeletal Diseases: Systematic Review With Best-Evidence Synthesis.

Background: Musculoskeletal diseases affect 1.71 billion people worldwide, impose a high biopsychosocial burden on patients, and are associated with high economic costs. The use of digital health interventions is a promising cost-saving approach for the treatment of musculoskeletal diseases.

Moderate evidence exists for four microRNAs as potential biomarkers for tendinopathies and degenerative tendon ruptures at the upper extremity in elderly patients: conclusion of a systematic review with best-evidence synthesis.

Purpose: The aim of this systematic review was to investigate tendon-specific microRNAs (miRNAs) as biomarkers for the detection of tendinopathies or degenerative tendon ruptures. Also, their regulatory mechanisms within the tendon pathophysiology were summarized.

Methods: A systematic literature research was performed using the PRISMA guidelines.

Physical match demands of four LIQUI-MOLY Handball-Bundesliga teams from 2019-2022: effects of season, team, match outcome, playing position, and halftime.

Introduction: Due to the development in team handball, there is a need to optimize the physical capacities of team handball players for which knowledge of the physical match demands is essential. The aim of this study was to investigate the physical match demands of four LIQUI-MOLY Handball-Bundesliga (HBL) teams across three seasons with respect to the effects of season, team, match outcome, playing position, and halftime.

Methods: A fixed installed local positioning system (Kinexon) was used, collecting 2D positional and 3D inertial measurement unit data at 20 and 100 Hz, respectively.