Publications by authors named "F Weerkamp"

Article Synopsis
  • - The study aimed to evaluate the need for exchange transfusions in neonatal care, track the use and waste of transfusion products, and understand their prevalence across the Netherlands.
  • - Data from all 9 neonatal intensive care units and 15 other hospitals were analyzed over an 11-year period, revealing that severe immune hemolysis was the most common reason for transfusions while around 50% of products ordered were not used.
  • - The findings showed that only 14.6 out of every 100,000 liveborn neonates required an exchange transfusion, indicating that these procedures are quite rare in the Netherlands and a significant number of products go unused.
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Background: Hemoglobinopathies, the most common inherited blood disorder, are frequently underdiagnosed. Early identification of carriers is important for genetic counseling of couples at risk. The aim of this study was to develop and validate a novel machine learning model on a multicenter data set, covering a wide spectrum of hemoglobinopathies based on routine complete blood count (CBC) testing.

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Anaemia can be subdivided into microcytic, normocytic and macrocytic categories, which give direction to the investigation to identify the cause of the anaemia. However, this is not always straightforward, as this case illustrates. A 73-year-old man with normocytic anaemia appeared to have both beta thalassemia trait (microcytic) and myelodysplastic syndrome (usually macrocytic).

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Introduction: Hemoglobin-based oxygen carriers, for example HBOC-201 (Hemopure), are aimed to bridge acute anemia when blood transfusion is not available or refused by the patient. However, since HBOC-201 appears free in plasma, it interferes with laboratory tests. This study presents an overview of HBOC-201 interference on four commonly used hematology analyzers and suggests treatment monitoring possibilities.

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