Publications by authors named "F Waldfahrer"
Background And Objective: The source data of four individual randomised, double-blind, reference- and/or placebo-controlled clinical trials with virtually identical study design were pooled for the present meta-analysis. The main objective was to further evaluate the efficacy and safety of the fixed combination of cinnarizine 20 mg and dimenhydrinate 40 mg in comparison to various other antivertigo treatments in patients suffering from central and/or peripheral vestibular vertigo.
Methods: Adult male and female outpatients were subjected to a 4-week treatment with the fixed combination of cinnarizine 20 mg and dimenhydrinate 40 mg, cinnarizine (20 mg, 50 mg), dimenhydrinate (40 mg, 100 mg), betahistine dimesylate (12 mg), betahistine dihydrochloride (16 mg) and placebo, respectively.
Article Synopsis
- The study aimed to improve pain management after tonsillectomy by comparing two methods: individual demand-based treatment vs. a fixed-schedule analgesic protocol.
- Forty patients were treated with each method, and pain levels, patient satisfaction, side effects, and medication needs were assessed post-surgery using a standardized questionnaire.
- Results showed no significant differences in pain levels or patient satisfaction between the two groups, indicating that current analgesic strategies for tonsillectomy may still be inadequate and require further refinement.
[Agranulocytosis after use of metamizole - an underestimated risk?].
Laryngorhinootologie
October 2020
Objective: Metamizole was the second most common drug prescribed in Germany in 2018 despite the known risk of agranulocytosis and the strict indication. According to Stammschulte et al. up to 25 % of all prescriptions are off-label use.
View Article and Find Full Text PDFThe BEMED study (BMJ 2016; 352: DOI 10.1136) was designed as multi-centric, double-blind, plaebo-controlled study in patients with Menière's disease. It should compare a low-level (2 × 24 mg/d) vs.
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