Publications by authors named "F W Price"
Purpose: To evaluate Descemet membrane endothelial keratoplasty (DMEK) for failed endothelial keratoplasty (EK).
Methods: We reviewed 362 consecutive DMEK cases for failed EK (Descemet stripping endothelial keratoplasty (DSEK) or DMEK), 118 for early EK failure, and 244 for late failure in 333 eyes of 323 patients without penetrating keratoplasty. Rejection and graft survival rates were assessed with Kaplan-Meier analysis.
Purpose: To identify areas of consensus among experts on the performance of endothelial keratoplasty by using a modified Delphi approach, to help create a framework for novice surgeons to adopt these procedures.
Methods: Thirty-one international experts in endothelial keratoplasty participated. Two rounds of electronic survey were followed by a hybrid, virtual meeting.
Experimental cell therapies for skeletal muscle conditions have shown little success, primarily because they use committed myogenic progenitors rather than true muscle stem cells, known as satellite cells. Here we present a method to generate in vitro-derived satellite cells (idSCs) from skeletal muscle tissue. When transplanted in small numbers into mouse muscle, mouse idSCs fuse into myofibers, repopulate the satellite cell niche, self-renew, support multiple rounds of muscle regeneration and improve force production on par with freshly isolated satellite cells in damaged skeletal muscle.
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- Descemet's Stripping Only (DSO) is a surgical technique that relies on the migration of corneal endothelial cells (CEnCs) to close wounds, and ripasudil, a ROCK inhibitor, may enhance this process.
- Research found that ripasudil significantly improves the migration and wound healing of both normal and Fuchs endothelial corneal dystrophy (FECD) cells, specifically boosting the activity of certain proteins associated with cell mobility.
- Ex vivo experiments showed that ripasudil treatment led to better migration and proliferation of CEnCs, suggesting it could be a valuable addition to DSO procedures by improving healing outcomes in the corneal environment.