The effect of surgical strategy in difficult cholecystectomy cases on postoperative complications outcome: a value-based healthcare comparative study.

Background: In patients undergoing laparoscopic cholecystectomy (LC) for complicated biliary disease, complication rates increase up to 30%. The aim of this study is to assess the effect of differences in surgical strategy comparing outcome data of two large volume hospitals.

Methods: A prospective database was created for all the patients who underwent a LC in two large volume hospitals between January 2017 and December 2018.

[Diagnostic image (208). A women with intermittant ileus].

A 87-year-old woman presenting with nausea, vomiting and lack of defaecation had a palpable mass in the left upper abdomen due to an intussusception of the terminal ileum into the transverse colon caused by a coecal adenocarcinoma.

Predictive effect of p53 and p21 alteration on chemotherapy response and survival in locally advanced adenocarcinoma of the esophagus.

Background: Cell cycle regulating proteins (p53/p21) and proliferation index Ki-67 have been associated with prognosis and response to chemotherapy. The aim of this study was to determine the significance of these molecular markers on tumor response and prognostic effect in a group of esophageal cancer patients treated with neoadjuvant chemotherapy.

Patients And Methods: Immunohistochemical expression of p53/p21 and Ki-67 was examined in pre-treatment biopsy specimen of 30 patients, in phase II neoadjuvant studies for locally advanced adenocarcinoma of the esophagus, who underwent surgery.

Perfusion of burn wounds assessed by laser doppler imaging is related to burn depth and healing time.

Average perfusion in various burn wounds was assessed using Laser Doppler Imaging (LDI). The time necessary for a complete healing of the wound was compared to the results of the LDI measurements. A certain depth of burn was associated with a typical pattern of perfusion in the course of time.

[Current estimate of the number of patients for liver transplantation with Dutch mortality figures].

Objective: To estimate the number of liver transplantations needed in the Netherlands, using death rates of the two periods 1979-1981 and 1989-1991.

Method: Death rates of different liver diseases were divided into: generally accepted indications (transplantable liver diseases, TLD), alcoholic liver cirrhosis, ALC and primary liver cell carcinoma, PLC. The death rates in the two periods, 1979-1981 and 1989-1991, were compared, and the impact of liver transplantation was determined.