High-dose intravenous immunoglobulins in HIV-1-infected adults with AIDS-related complex and Walter-Reed 5.

The influence of high-dose intravenous immunoglobulins (HD-IVIG) on the clinical status and T4 cell count of adults with AIDS-related complex (ARC) and Walter-Reed 5 (WR5) was evaluated in a randomized double-blind longitudinal study. Inclusion criteria were: (1) T4 cells less than 400/microliters and (2a) oral thrush or cutaneous anergy or (2b) two clinical ARC criteria (fever, diarrhea, weight loss, fatigue, night sweats). Thirty patients [28 males, 2 females, median age 41 (24-64) years] with ARC (n = 8), WR5 (n = 12) and both (n = 10) were stratified according to their T4 cell count (greater than or equal to vs.

[Detection of fibrinolytic split products in patient collections with disordered hemostasis. I. In pathologically verified lung cancer. II. In thrombotic/embolic occurrences].

56 patients afflicted with pathologically-histologically ensured carcinoma of the lungs and bronchial system as well as 15 patients with thrombotic/embolic processes under streptokinase therapy were examined for defects in their coagulation system and for fibrinogen split products by using methods of reptilase time (RPZ) and staphylococcal clumping test (SCT). 1. Quantitatively more split products could be identified in patients after surgery and in those without any specific therapy than in patients under irradiation and chemotherapy.

[The relevance of schizocyte demonstration for the diagnosis of rejection in patients with transplanted kidneys].

Schizocytes may be obtained, if erythrocytes are being pressed through glassfibre threads under pressure. For the purpose of explaining the different mechanisms of schizocytes origin, model tests were made in the haemoresistometer according to Fleisch and in the shaking water bath. As schizocytes can easily be identified, they will yield valuable differential-diagnostical informations and will give a high evidence in checking the progress of transplanted patients.

[The demonstration of HL-A antigens on thrombocytes under various conditions].

Platelets of healthy test persons were gained according to the method of Aster (avital cells) and according to the procedure of BUBE and GMURZYNSKI (vital cells). Because of their tendency towards aggregation vital cells do bind any HL-A antibodies and whereas avital cells will fix antibodies and complement depending on the height of the titre. Thrombocytes stored in the own serum will respond less to the micro-C'-fixation test at + 4 degrees C as well as--196 degrees C, whereas storage in NaN3/NaCl and under the conditions of the own serum will reveal no differences up to--196 degrees C in each case.