Publications by authors named "F W Allendorf"

There are two primary measures of the amount of genetic variation in a population at a locus: heterozygosity and the number of alleles. Effective population size ( ) provides both an expectation of the amount of heterozygosity in a population at drift-mutation equilibrium and the rate of loss of heterozygosity because of genetic drift. In contrast, the number of alleles in a population at drift-mutation equilibrium is a function of both and census size ( ).

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The sympatric existence of genetically distinguishable populations of the same species remains a puzzle in ecology. Coexisting salmonid fish populations are known from over 100 freshwater lakes. Most studies of sympatric populations have used limited numbers of genetic markers making it unclear if genetic divergence involves certain parts of the genome.

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Article Synopsis
  • The study focuses on perfluoroalkyl acids (PFAAs), which are ionic compounds known for their harmful accumulative behavior in the environment.
  • Researchers performed model calculations to understand the distribution of PFAAs and their alternatives in different mammalian organs by comparing these models to actual measurements from humans and rats.
  • Results indicated that albumin and membrane lipids have the highest capacity to absorb PFAAs, while storage lipids play a minor role, and sorption to fatty acid binding protein is mainly significant for short-chain PFAAs.
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Article Synopsis
  • Researchers are exploring alternatives to perfluoroalkyl acids (PFAAs) to reduce bioaccumulation, using experiments to study the behavior of various perfluoroalkyl compounds.
  • They conducted dialysis experiments to measure partition coefficients and assessed passive permeation into cells through lipid bilayers.
  • The findings indicate that the permeation of both neutral and anionic species can affect the toxicity of PFAAs, leading to a proposed new model for predicting pH-dependent baseline toxicity.
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