Evidence-based organization and patient safety strategies in European hospitals.

Objective: To explore how European hospitals have implemented patient safety strategies (PSS) and evidence-based organization of care pathway (EBOP) recommendations and examine the extent to which implementation varies between countries and hospitals.

Design: Mixed-method multilevel cross-sectional design in seven countries as part of the European Union-funded project 'Deepening our Understanding of Quality improvement in Europe' (DUQuE).

Setting And Participants: Seventy-four acute care hospitals with 292 departments managing acute myocardial infarction (AMI), hip fracture, stroke, and obstetric deliveries.

Volume and diagnosis: an approach to cross-border care in eight European countries.

Objectives: Mobility of patients is a pertinent issue on the European Union's agenda. This study aimed to estimate the volume and main diagnoses of cross-border care in eight European countries, in order to provide policy makers with background information about the nature of patient mobility in Europe.

Methods: This article reports the combined findings from three independent studies that compiled self-reported information on admissions data and main diagnoses from more than 200 hospitals in eight European countries.

[The effect of methotrexate on activity of T-lymphocyte marker enzymes in patients with psoriasis vulgaris].

Radiochromatographic methods were used in order to ascertain the activity of adenosinedeaminase and purinnucleoside phosphorylase in lymphocytes isolated from the venous blood of 32 patients with psoriasis vulgaris in comparison with enzyme activities in 28 clinically healthy subjects. 11 selected patients with a severe form of psoriasis were subdued to therapy by means of methotrexate and its effect on the activity of these enzymes was investigated. Untreated patients yielded a statistically significant increase in the activities of adenosinedeaminase and purinnucleoside phosphorylase in comparison to the control group of healthy subjects.

Reduced expression of HLA-DP antigens on PWM stimulated T lymphocytes in patients suffering from psoriasis vulgaris.

24 psoriasis vulgaris patients were investigated for the expression of class II HLA antigens on the surface of PWM-stimulated T lymphocytes. The percentage of the expression of HLA-DP antigens ranged from 50.1% to 82.