[Glyphosate and human health].

At this time of environmental crisis, pesticides represent a major threat to the environment and to human health alike. The widely used herbicide glyphosate is suspected of acting as a mutagen, a carcinogen as well as a neurotoxic substance for the professionals who use it. This possibly also holds true for the population at large.

[Diagnostic approach in primary care - Role of intuition, cognition, clinical data and other determinants].

This prospective observational study evaluated the diagnostic approach followed by 59 GPs of Western Switzerland in 672 patients with chest pain. The approach common for all GP begins with a very rapid assessment of the threat and of the etiology of the condition. This intuitive estimate allows for an analytical process by means of history, physical and, in half of the cases, paraclinical or specialist examination and is influenced by the hazard of the condition, the difficulty of the diagnosis, the concern, the gender, and the personality of both patients and GPs.

Sex/gender bias in the management of chest pain in ambulatory care.

Objective: Cardiovascular diseases (CVD) are the main cause of death worldwide and despite a higher prevalence in men, mortality from CVD is higher among women. Few studies have assessed sex differences in chest pain management in ambulatory care. The objective of this post hoc analysis of data from a prospective cohort study was to assess sex differences in the management of chest pain in ambulatory care.

Development of mental disorders one year after exposure to psychosocial stressors; a cohort study in primary care patients with a physical complaint.

Background: Mental disorders, common in primary care, are often associated with physical complaints. While exposure to psychosocial stressors and development or presence of principal mental disorders (i.e.

Development and validation of a clinical prediction rule for chest wall syndrome in primary care.

Background: Chest wall syndrome (CWS), the main cause of chest pain in primary care practice, is most often an exclusion diagnosis. We developed and evaluated a clinical prediction rule for CWS.

Methods: Data from a multicenter clinical cohort of consecutive primary care patients with chest pain were used (59 general practitioners, 672 patients).