Publications by authors named "F Vecchi"
Periprosthetic joint infection (PJI) is a leading cause and major complication of joint replacement failure. As opposed to standard-of-care systemic antibiotic prophylaxis for PJI, we developed and tested titanium femoral intramedullary implants with titania nanotubes (TNTs) coated with the antibiotic gentamicin and slow-release agent chitosan through electrophoretic deposition (EPD) in a mouse model of PJI. We hypothesized that these implants would enable local gentamicin delivery to the implant surface and surgical site, effectively preventing bacterial colonization.
View Article and Find Full Text PDF: Tendinopathy of the gluteus medius and minimus tendons is a primary source of lateral hip pain, ranging from interstitial and partial-thickness tears to complete tears. Treatments include muscle transfers, Achilles tendon allograft procedures, and primary repairs with allografts. This study evaluated the one-year outcomes of gluteus medius and minimus reconstruction using an open double-row technique with a partial tensor fasciae latae transfer for severe Trendelenburg post-total hip arthroplasty.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the effectiveness of wearable cardioverter defibrillators (WCD) versus early implantable cardioverter defibrillators (ICD) for preventing sudden cardiac death in patients with reduced ejection fraction.
- Out of 41 patients, results showed similar rates of arrhythmias and heart function recovery between the WCD and early ICD groups during the waiting period.
- The use of WCD was found to be more cost-effective, saving about 19.9% per patient in the short term and projected even greater savings over ten years while effectively selecting candidates for ICD implantation.
Closed loop stimulation in left bundle branch area pacing.
Pacing Clin Electrophysiol
September 2024
Introduction: Closed Loop Stimulation (CLS) is a rate-responsive algorithm that adjusts heart rate (HR) based on changes in intracardiac impedance measured from the right ventricle lead. However, the use of CLS in conduction system pacing has not been investigated. In this retrospective study, we aimed to assess whether CLS with left bundle branch area pacing (LBBAP) can generate an appropriate distribution of HR in daily life.
View Article and Find Full Text PDFBackground: In patients with a type 2 or 3 Brugada pattern, the pharmacological (IC drugs) induction of a type 1 pattern confirms the diagnosis of Brugada syndrome.
Objective: To evaluate the value of various ECG markers in predicting IC drug test results.
Methods: We retrospectively analysed 443 consecutive patients referred to our Center (from January 2010 to December 2019) to undergo Ajmaline/Flecainide testing; all had a type 2 or 3 Brugada pattern or were relatives with Brugada syndrome.