Publications by authors named "F Varenne"
[Six-month real-world outcomes of intravitreal clindamycin for ocular toxoplasmosis].
J Fr Ophtalmol
December 2024
Objective: To evaluate in a real-world setting an intravitreal clindamycin treatment protocol for ocular toxoplasmosis.
Methods: This was a single-center, retrospective review with a 6-month follow-up. Our protocol proposed an IVT of clindamycin as first-line treatment, and management was chosen according to the patient's status (past medical history of ocular toxoplasmosis or not).
Article Synopsis
- Optic Atrophy (OA) can lead to microcystic macular edema (MME) in the retinal inner nuclear layer, with a study investigating its prevalence in non-glaucomatous OA patients over five years.
- Out of 643 eyes examined, 15% developed MME, with varying prevalence depending on the underlying cause of OA, except for toxic/nutritional factors.
- MME was linked to thinning of the ganglion cell and nerve fiber layers, reduced visual acuity, and INL thickening, but its presence does not help in diagnosing OA conditions.
Article Synopsis
- There is a very rare condition where people have early-onset ataxia (which means difficulty with movement) and miosis (which means their pupils are very small).
- So far, only one family has been identified with this condition, and they found a specific change in a gene called ITPR1 that seems to cause it.
- Researchers found another person with a similar change in the same gene, which helps to confirm that this gene is linked to the ataxia and miosis syndrome, making it easier for doctors to recognize and diagnose in the future.