Publications by authors named "F Vannini"
Sudden cardiac death (SCD) prevention in cardiomyopathies such as hypertrophic (HCM), dilated (DCM), non-dilated left ventricular (NDLCM), and arrhythmogenic right ventricular cardiomyopathy (ARVC) remains a crucial but complex clinical challenge, especially among younger populations. Accurate risk stratification is hampered by the variability in phenotypic expression and genetic heterogeneity inherent in these conditions. This article explores the multifaceted strategies for preventing SCD across a spectrum of cardiomyopathies and emphasizes the integration of clinical evaluations, genetic insights, and advanced imaging techniques such as cardiac magnetic resonance (CMR) in assessing SCD risks.
View Article and Find Full Text PDFPurpose: When dealing with the health status of the knee articular surface, the entire osteochondral unit has gained increasing attention, and in particular the subchondral bone, which plays a key role in the integrity of the osteochondral unit. The aim of this article was to discuss the current evidence on the role of the subchondral bone.
Methods: Experts from different geographical regions were involved in performing a review on highly discussed topics about the subchondral bone, ranging from its etiopathogenetic role in joint degeneration processes to its prognostic role in chondral and osteochondral defects, up to treatment strategies to address both the subchondral bone and the articular surface.
Background: The purpose of this study was to assess the long-term clinical efficacy of first-generation autologous chondrocyte implantation (ACI) technique for osteochondral lesions of the ankle joint.
Methods: Eleven patients with symptomatic OLTs underwent ACI from December 1997 to October 2002. A total of 9 patients (5 men, 4 women, age 25.
Sex does not influence the long-term outcome of matrix-assisted autologous chondrocyte transplantation.
Knee Surg Sports Traumatol Arthrosc
October 2024
Article Synopsis
- This study explores the long-term effects of sex on the clinical outcomes of regenerative procedures for knee cartilage repairs using matrix-assisted autologous chondrocyte transplantation (MACT) in 235 patients, with a follow-up averaging 14 years.
- Results show that men had a significantly lower failure rate (10.7%) compared to women (28.8%) and higher overall knee function scores, but when comparing matched groups of men and women, outcomes were similar.
- The research highlights that women tend to have more complex lesion patterns, making their recovery from knee cartilage repair more challenging despite both sexes experiencing improvements over time.