Publications by authors named "F Van den Bergh"
Abdominal aortic aneurysms (AAAs) are a degenerative aortic disease and associated with hallmarks of aging, such as mitophagy. Despite this, the exact associations among mitophagy, aging, and AAA progression remain unknown. In our study, gene expression analysis of human AAA tissue revealed downregulation of mitophagy pathways, mitochondrial structure, and function-related proteins.
View Article and Find Full Text PDFArticle Synopsis
- Sinusoidal obstruction syndrome (SOS) is a serious complication often seen in patients undergoing hematopoietic stem cell transplantation, with severe cases having a high mortality rate.
- A 27-year-old woman with acute myeloid leukemia developed a severe form of SOS after chemotherapy, leading to multiple organ failure.
- She was successfully treated using a combination of urgent medical procedures, including the insertion of a transjugular intrahepatic portosystemic shunt (TIPS) and medication, highlighting the need for better prevention and risk factor identification.
Article Synopsis
- * Data from 459 patients with vessel perforation showed a 90-day mortality rate of 51.9%, with only 16.3% achieving a favorable recovery (mRS 0-2).
- * The findings indicate that large vessel perforation leads to worse outcomes, while thrombolysis doesn’t worsen prognoses; quick management of bleeding is crucial for survival.
The adult mammalian heart has limited regenerative capacity following injury, leading to progressive heart failure and mortality. Recent studies have identified the spiny mouse ( ) as a unique model for mammalian cardiac isch3emic resilience, exhibiting enhanced recovery after myocardial infarction (MI) compared to commonly used laboratory mouse strains. However, the underlying cellular and molecular mechanisms behind this unique response remain poorly understood.
View Article and Find Full Text PDF