Effect of caricapryl-99 seed alkaloid extract on the serum levels of sex hormones and pituitary gonadotrophins in male albino rats.

Activity of alkaloid extract of caricapryl-99 seeds [Carica papaya Linn seeds] on the serum levels of steroid hormones was studied in adult male albino rats. Three tolerated doses obtained from the graph of percentage toxicity [10, 50 and 150 mg/kg] were separately administered orally, daily for three days to three groups of male rats [n=5] while group four of 5 rats received the vehicle [corn oil] as control. The results showed that 10 mg/kg/d caused increase serum levels of FSH and estrogen but decrease in the serum levels of LH and testosterone compared to control; 50 mg/kg/d elevated the serum levels of FSH, estrogen but inhibited testosterone; while 150 mg/kg/d pretreatments caused a significant decrease [p<0.

Effects of Carica papaya (paw paw) seeds extract on the morphology of pituitary-gonadal axis of male Wistar rats.

The effects of oral administration of Carica papaya seeds extract on the morphology of pituitary, testes and sex accessory glands were studied. The C. papaya extract (50 and 200 mg/kg/day) was administered orally to sexually mature male Wistar rats for 1 and 8 weeks, respectively.

Activity of aqueous extract of the bark of Vitex doniana on uterine muscle response to drugs.

The activity of Vitex doniana on the uterine muscle response was investigated. The bark of Vitex doniana was extracted in boiled water at 100 degrees C, and the extracted solution filtered and centrifuged with refrigeration. The extract prepared from the dry powder extract was tested on uterine muscle strip preparations.

Hepatotoxicity of the Methanol Extract of Carica papaya. (Paw-Paw) Seeds in Wistar Rats.

Activity of Carica papaya. Linn. (commonly known as paw-paw.

Effects of stem bark and leaf extracts of Bridelia ferruginea on rat bladder smooth muscle.

The effects of ethanol extracts of Bridelia ferruginea leaves and stem bark on purinergic neurotransmission in the rat bladder were investigated. The stem bark extract potentiated the contraction of the bladder evoked by exogenous adenosine 5-triphosphate (ATP) but depressed KCl-induced contractions in a dose-related pattern; these two opposite actions might account for the lack of effect on field stimulation of the bladder purinergic nerves. The leaf extract depressed purinergic nerve-mediated contraction of the rat bladder in a dose-related fashion.