Publications by authors named "F U Jianhua"
Article Synopsis
- The study investigates the effects of Qingfei Zhisou (QFZS) oral liquid on body temperature regulation and inflammatory factors in rats induced with fever.
- Researchers established a fever model using dry yeast and divided rats into different treatment groups to assess QFZS's impact on body temperature and inflammatory proteins.
- Results indicated that QFZS effectively lowered body temperature and reduced levels of inflammatory markers, suggesting its anti-inflammatory and anti-pyrexia actions may involve the metabolism of specific lipids and regulation of ion channels related to inflammation.
Preterm birth is a public health priority worldwide, with approximately 15 million premature babies born each year. Oxygen supplementation is one of the most common interventions for preterm infants. However, prolonged oxygen inhalation at supraphysiological concentrations can lead to the development of bronchopulmonary dysplasia (BPD).
View Article and Find Full Text PDFEpilepsy is one of the most common disorders in children, with an incidence rate of approximately 5%. Although an increasing number of genes have been demonstrated to be pathogenic factors in epilepsy, evidence for a potential pathogenic role of ATP6V1A remains limited. Herein, the clinical and genetic data of a 5-year-old boy who experienced seizures at 9 months of age are collected.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how altered levels of O-GlcNAc influence damage to alveolar type II cells under hyperoxia, linking it to bronchopulmonary dysplasia (BPD).
- Researchers treated RLE-6TN cells with inhibitors and metabolic donors to assess changes in cell viability, metabolism, and apoptosis caused by hyperoxia.
- Findings indicate that reduced O-GlcNAc levels contribute to cell injury, while inhibiting its synthesis may protect against hyperoxia-induced damage and improve cell function.
Bronchopulmonary dysplasia (BPD) is a common devastating pulmonary complication in preterm infants. Supplemental oxygen is a lifesaving therapeutic measure used for premature infants with pulmonary insufficiency. However, oxygen toxicity is a significant trigger for BPD.
View Article and Find Full Text PDF