Publications by authors named "F Torricelli"
Purpose: This prospective study aimed to identify risk factors associated with progression to stage 3 chronic kidney disease (CKD) and the occurrence of kidney stone formation or growth following nephrectomy for urolithiasis.
Materials And Methods: From January 2006 to May 2013, patients undergoing nephrectomy for urolithiasis were enrolled. Renal function was assessed using estimated glomerular filtration rate (eGFR) via the Chronic Kidney Disease Epidemiology Collaboration equation, while kidney stone events were detected using computed tomography.
The advent of "omics" technologies for high-depth tumor profiling has provided new information regarding cancer heterogeneity. However, a bulk omics profile can only partially reproduce tumor complexity, and it does not meet the preferences of pathologists used to perform an in situ assessment of marker expression, for instance, with immunohistochemistry. The NanoString GeoMx® Digital Spatial Profiler (DSP) is a platform for morphology-guided multiplex profiling of tissue slides, which allows the digital quantification of target analytes in different neoplastic settings.
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- The study aimed to compare two classification systems, the Comprehensive Complication Index (CCI) and the Clavien-Dindo classification (CDC), in elderly patients undergoing percutaneous nephrolithotomy (PCNL) and to find out what factors predict complications post-surgery.
- In a retrospective analysis of 244 patients aged 60 and older, 15.6% experienced complications within 30 days of surgery, with length of hospital stay and emergency room admissions showing a significant correlation with both classification systems.
- Although CDC and CCI were equally effective in predicting hospital stay and ER visits, CDC underestimated hospitalization costs compared to CCI, and certain factors like higher ASA physical status, comorbidity index, and
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- A meta-analysis was conducted to evaluate the effectiveness of Reverse Trendelenburg (RevTren) and Trendelenburg (Tren) surgical positions versus standard dorsal lithotomy in reducing ureteral stone migration during ureteroscopic laser lithotripsy.
- The study reviewed 137 articles, ultimately including 8 that involved 1,374 patients, highlighting that RevTren significantly reduced stone migration and improved success rates, while Tren increased stone success despite promoting migration to upper calyces.
- Both alternative positions offer notable benefits over the standard method without increasing complications, suggesting they can be safely integrated into clinical practice for better patient outcomes.
A "watch and wait" strategy, delaying treatment until active disease manifests, is adopted for most CLL cases; however, prognostic models incorporating biomarkers have shown to be useful to predict treatment requirement. In our prospective O-CLL1 study including 224 patients, we investigated the predictive role of 513 microRNAs (miRNAs) on time to first treatment (TTFT). In the context of this study, six well-established variables (i.
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