Publications by authors named "F Tonucci"

() can persist in food processing environments (FPEs), surviving environmental stresses and disinfectants. We described an intensive environmental monitoring plan performed in Central Italy and involving food producing plants (FPPs) and retail grocery stores (RSs). The aim of the study was to provide a snapshot of the circulation in different FPEs during a severe listeriosis outbreak, using whole genome sequencing (WGS) to investigate the genetic diversity of the isolated, evaluating their virulence and stress resistance profiles.

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Article Synopsis
  • The public health risk of ready-to-eat (RTE) foods is influenced by how well contamination is controlled during production and varies by the specific strain of pathogens present.
  • Current analytical methods can only identify and quantify pathogens at the species level, not differentiating between harmful and less harmful strains.
  • A recent outbreak of listeriosis in Italy led to enhanced surveillance methods, including the development of a new multiplex PCR technique to detect specific virulence genes, improving food safety assessments.
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CDC42 interacting protein 4 (CIP4) is a CDC42 effector that coordinates membrane deformation and actin polymerization. The correlation of CIP4 overexpression with metastatic capacity has been characterized in several types of cancer. However, little information exists on how CIP4 function is regulated.

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Hákarl is produced by curing of the Greenland shark (Somniosus microcephalus) flesh, which before fermentation is toxic due to the high content of trimethylamine (TMA) or trimethylamine N-oxide (TMAO). Despite its long history of consumption, little knowledge is available on the microbial consortia involved in the fermentation of this fish. In the present study, a polyphasic approach based on both culturing and DNA-based techniques was adopted to gain insight into the microbial species present in ready-to-eat hákarl.

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