Publications by authors named "F Tomassini"

Background: Prompt reperfusion is critical for patients with ST-segment elevation myocardial infarction (STEMI) to improve outcomes. Yet, variability in regional healthcare delivery may influence treatment times and patient outcomes. We thus aimed at evaluating differences in management and outcomes of STEMI patients across Northern, Central, and Southern Italy, focusing on time-dependent reperfusion and in-hospital logistics.

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  • A study evaluated the effectiveness of closing a patent foramen ovale (PFO) after a cryptogenic stroke, comparing those who had it done within 9 months (early closure) to those who had it done after 9 months (delayed closure).
  • The research found no significant differences in recurrence rates of cerebrovascular events or systemic embolisms between the early and delayed closure groups, indicating similar outcomes regardless of when the procedure was performed.
  • The results suggest that PFO closure might be beneficial even in patients with a cryptogenic event that occurred more than 9 months ago, challenging the notion that the timing of the closure is critical.
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  • - The study aims to compare immediate versus staged percutaneous coronary intervention (PCI) strategies for patients with aneurysmatic right coronary artery (ARCA) during acute coronary syndrome (ACS), analyzing outcomes from 85 patients.
  • - Results show that both PCI strategies had similar rates of procedural success and long-term outcomes, but the staged approach led to a higher incidence of bleeding and longer hospital stays.
  • - The findings suggest that while both methods are viable, immediate PCI might be preferable due to lower complications and shorter hospital duration.
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The recent results of the REVIVED-BCIS2 randomized clinical trial added further controversy on the utility of myocardial revascularization in patients with chronic coronary syndrome with reduced ejection fraction. However, coronary artery disease still represents the leading cause of heart failure with reduced ejection fraction, with the potential for functional recovery following complete revascularization due to the restoration of the so-called hibernating myocardium. We report an emblematic case of a patient with recovery of contractile function and normalization of the left bundle branch block after percutaneous coronary intervention of the right coronary artery chronic total occlusion.

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  • The study examines the effectiveness of the J-CTO channel score in predicting microcatheter tracking success during retrograde CTO-PCI procedures.
  • It involved 189 patients and found that small-sized and tortuously-shaped septal collaterals significantly increased the risk of microcatheter tracking failure (MTF).
  • Patients who experienced MTF had a much lower success rate in procedures and a higher risk of complications compared to those with successful microcatheter tracking.
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