Publications by authors named "F Thivolet-Bejui"
Nintedanib in idiopathic and secondary pleuroparenchymal fibroelastosis.
Orphanet J Rare Dis
October 2021
Background: Pleuroparenchymal fibroelastosis (PPFE) has a variable disease course with dismal prognosis in the majority of patients with no validated drug therapy. This study is to evaluate the effect of nintedanib in patients with idiopathic and secondary PPFE. Patients admitted to a tertiary care center (2010-2019) were included into this retrospective analysis if they had a multidisciplinary diagnosis of PPFE, had been followed-up for 3 months or more, and had lung function tests and chest CTs available for review.
View Article and Find Full Text PDFTo investigate the clinical characteristics, epidemiology, survival estimates and healthcare resource utilization and associated costs in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD) in France. The French national administrative healthcare database, the Système National des Données de Santé (SNDS), includes data on 98.8% of the French population, including data relating to ambulatory care, hospitalizations and death.
View Article and Find Full Text PDFBackground: There is a paucity of data on the epidemiology, survival estimates and healthcare resource utilisation and associated costs of patients with progressive fibrosing interstitial lung disease (PF-ILD) in France. An algorithm for extracting claims data was developed to indirectly identify and describe patients with PF-ILD in the French national administrative healthcare database.
Methods: The French healthcare database, the Système National des Données de Santé (SNDS), includes data related to ambulatory care, hospitalisations and death for 98.
Article Synopsis
- Infective endocarditis (IE) is a serious condition that requires proper identification of pathogens for effective treatment, but 5.2% of cases remain unresolved in terms of microbial identification.
- A study was conducted in France, utilizing an ultra-sensitive method to detect microbial DNA in cardiac samples from patients previously diagnosed with definite IE, specifically focusing on cases where conventional methods failed to identify pathogens.
- The results showed successful detection of microbial DNA in all 16 cases of microbiologically nondocumented IE, revealing Malassezia restricta in some patients, highlighting its potential as an overlooked cause and the risk of misdiagnosis due to its cross-reactivity with Candida albicans.
Background: Video-assisted surgical lung biopsy (SLB) is performed in 10-30% of cases to establish the diagnosis of idiopathic pulmonary fibrosis (IPF).
Objectives: The aim of the study was to analyze the impact of SLB on lung function in patients eventually diagnosed with IPF.
Methods: This is an observational, retrospective, monocentric study of all consecutive patients eventually diagnosed with IPF in multidisciplinary discussion who underwent SLB over 10 years in a specialized center.