Long-range trajectory reconstructions using the point mass model.

In shooting incident reconstructions, forensic examiners usually deal with scenes involving short-range trajectories, typically ≤30 m. In situations such as this, a linear trajectory reconstruction model is appropriate. However, a forensic expert can also be asked to estimate a shooter's position by reconstructing a long-range trajectory where the bullet's path becomes arced as a result of gravity and the greater time in flight.

Nano-Hydroxyapatite toothpaste of rice field snail shell combined with basil leaf extract as a remineralizing and antibacterial agent to prevent dental caries.

Background: This study aimed to compare rice snail shell nano-hydroxyapatite (nano-HAp) toothpaste combined with basil leaf extract and 1450 ppm fluoridated herbal toothpaste as remineralizing and antibacterial agents.

Material And Methods: Experimental toothpastes were prepared with different concentrations of nano-HAp (5% nano-HAp, 10% nano-HAp) and a fixed concentration of basil leaf extract (5% extract). 24 bovine tooth enamel samples were divided into 4 treatment groups.

Prediction of tumor response to neoadjuvant chemotherapy in high-grade osteosarcoma using clustering-based analysis of magnetic resonance imaging: an exploratory study.

Purpose: To evaluate the ability of magnetic resonance imaging (MRI)-based clustering analysis to predict the pathological response to neoadjuvant chemotherapy (NACT) in patients with primary high-grade osteosarcoma.

Materials And Methods: Twenty-two patients were included in this retrospective study. All patients underwent MRIs before and after NACT.

[The evolution of a luminal breast cancer to a triple-negative and its impact on disease control with sacituzumab govitecan.].

Triple negative breast cancer (TNBC) represents 15% of invasive breast cancer cases and is an aggressive subtype. Patients with metastatic TNBC have a poor prognosis. Efforts have been made to develop new therapeutic options and identify molecular biomarkers to improve overall survival and quality of life for TNBC patients.