Head and Neck Rhabdomyosarcoma in Pediatric Patients: An International Collaborative Study.

Background: Rhabdomyosarcoma (RMS), a rare malignant tumor, frequently affects pediatric patients, with 35%-40% occurring in the head and neck. This study analyzes the clinicopathologic profile of pediatric head and neck rhabdomyosarcomas from Brazil, Guatemala, Mexico, and South Africa.

Methods: We reviewed 44 cases from 10 Oral and Maxillofacial Pathology services, conducting immunohistochemical analyses of desmin, myogenin, Myo-D1, and Ki67, with quantification via QuPath software.

Mercury removal from mining wastewater by bioaccumulation and thermal separation in Eichhornia crassipes.

Environmental problems persist due to mercury from artisanal and small-scale gold mining (ASGM) as well as ecological problems associated with the macrophyte Eichhornia crassipes Martius (EC). Environmental problems persist due to mercury contamination from artisanal and small-scale gold mining (ASGM) and ecological issues related to the macrophyte Eichhornia crassipes Martius (EC). A bioaccumulation study was conducted on mercury-laden wastewater (WWm) from ASGM using a pilot treatment plant, specifically a constructed wetland system (CW) with the macrophyte species EC.

Effects of 3-day fasting on secretory IgA concentration in the saliva and lymphotoxin alpha expression in healthy volunteers: a proof of concept study.

Background: animal studies have shown that enteral stimuli play an important role in modulating gut-associated lymphoid tissue.

Objective: the main objectives of this study were 1) to evaluate the effect of 3-day fasting on secretory immunoglobulin A (S-IgA) in parotid saliva and 2) to determine the levels of lymphotoxin (LT) transcription in peripheral blood mononuclear cells (PBMNC) from healthy volunteers as a proxy for studying GALT health.

Methods: these adult volunteers had fasted for three days as part of a cultural ritual.

A pause in the weakening of the Atlantic meridional overturning circulation since the early 2010s.

The current state-of-the-art climate models when combined together suggest that the anthropogenic weakening of the Atlantic Meridional Overturning Circulation (AMOC) has already begun since the mid-1980s. However, continuous direct observational records during the past two decades have shown remarkable resilience of the AMOC. To shed light on this apparent contradiction, here we attempt to attribute the interdecadal variation of the historical AMOC to the anthropogenic and natural signals, by analyzing multiple climate and surface-forced ocean model simulations together with direct observational data.